# AD-Lite Net: A Lightweight and Concatenated CNN Model for Alzheimer's Detection from MRI Images

arXiv: https://arxiv.org/abs/2409.08170 · HTML: https://mlsanity.com/paper/2409.08170/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 38 references that are in the map.
- First posted on arXiv 12 Sep 2024.

## Builds on (most cited first, 9 of 9)

- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Vision Transformers for Dense Prediction](https://mlsanity.com/paper/2103.13413/) (2021)
- [Geometric deep learning: going beyond Euclidean data](https://mlsanity.com/paper/1611.08097/) (2016)
- [Rethinking Spatial Dimensions of Vision Transformers](https://mlsanity.com/paper/2103.16302/) (2021)
- [A Recurrent Vision-and-Language BERT for Navigation](https://mlsanity.com/paper/2011.13922/) (2020)
- [Machine Learning Models that Remember Too Much](https://mlsanity.com/paper/1709.07886/) (2017)
- [Self-Supervised Learning with Swin Transformers](https://mlsanity.com/paper/2105.04553/) (2021)
- [A Deep Multi-Level Network for Saliency Prediction](https://mlsanity.com/paper/1609.01064/) (2016)

## Built on by (most cited first, 3 of 3)

- [Fibonacci-Net: A Lightweight CNN model for Automatic Brain Tumor Classification](https://mlsanity.com/paper/2503.13928/) (2025)
- [Novel Pooling-based VGG-Lite for Pneumonia and Covid-19 Detection from Imbalanced Chest X-Ray Datasets](https://mlsanity.com/paper/2504.07468/) (2025)
- [MSAD-Net: Multiscale and Spatial Attention-based Dense Network for Lung Cancer Classification](https://mlsanity.com/paper/2504.14626/) (2025)

## Abstract (arXiv)

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of Alzheimer's disease from MRI images is fraught with less sensitivity and it is a very tedious process for neurologists. Therefore, there is a need for an automatic Computer Assisted Diagnosis (CAD) system, which can detect AD at early stages with higher accuracy. In this research, we have proposed a novel AD-Lite Net model (trained from scratch), that could alleviate the aforementioned problem. The novelties we bring here in this research are, (I) We have proposed a very lightweight CNN model by incorporating Depth Wise Separable Convolutional (DWSC) layers and Global Average Pooling (GAP) layers. (II) We have leveraged a ``parallel concatenation block'' (pcb), in the proposed AD-Lite Net model. This pcb consists of a Transformation layer (Tx-layer), followed by two convolutional layers, which are thereby concatenated with the original base model. This Tx-layer converts the features into very distinct kind of features, which are imperative for the Alzheimer's disease. As a consequence, the proposed AD-Lite Net model with ``parallel concatenation'' converges faster and automatically mitigates the class imbalance problem from the MRI datasets in a very generalized way. For the validity of our proposed model, we have implemented it on three different MRI datasets. Furthermore, we have combined the ADNI and AD datasets and subsequently performed a 10-fold cross-validation experiment to verify the model's generalization ability. Extensive experimental results showed that our proposed model has outperformed all the existing CNN models, and one recent trend Vision Transformer (ViT) model by a significant margin.
