# SAN: Hypothesizing Long-Term Synaptic Development and Neural Engram Mechanism in Scalable Model's Parameter-Efficient Fine-Tuning

arXiv: https://arxiv.org/abs/2409.06706 · HTML: https://mlsanity.com/paper/2409.06706/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 34 of its 67 references that are in the map.
- First posted on arXiv 24 Aug 2024.

## Builds on (most cited first, 30 of 34)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Think you have Solved Question Answering? Try ARC, the AI2 Reasoning Challenge](https://mlsanity.com/paper/1803.05457/) (2018)
- [HellaSwag: Can a Machine Really Finish Your Sentence?](https://mlsanity.com/paper/1905.07830/) (2019)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [PIQA: Reasoning about Physical Commonsense in Natural Language](https://mlsanity.com/paper/1911.11641/) (2019)
- [Making the V in VQA Matter: Elevating the Role of Image Understanding in Visual Question Answering](https://mlsanity.com/paper/1612.00837/) (2016)
- [BoolQ: Exploring the Surprising Difficulty of Natural Yes/No Questions](https://mlsanity.com/paper/1905.10044/) (2019)
- [Can a Suit of Armor Conduct Electricity? A New Dataset for Open Book Question Answering](https://mlsanity.com/paper/1809.02789/) (2018)
- [MMBench: Is Your Multi-modal Model an All-around Player?](https://mlsanity.com/paper/2307.06281/) (2023)
- [Learn to Explain: Multimodal Reasoning via Thought Chains for Science Question Answering](https://mlsanity.com/paper/2209.09513/) (2022)
- [CommonsenseQA: A Question Answering Challenge Targeting Commonsense Knowledge](https://mlsanity.com/paper/1811.00937/) (2018)
- [Evaluating Object Hallucination in Large Vision-Language Models](https://mlsanity.com/paper/2305.10355/) (2023)
- [Towards VQA Models That Can Read](https://mlsanity.com/paper/1904.08920/) (2019)
- [Visual Prompt Tuning](https://mlsanity.com/paper/2203.12119/) (2022)
- [EuroSAT: A Novel Dataset and Deep Learning Benchmark for Land Use and Land Cover Classification](https://mlsanity.com/paper/1709.00029/) (2017)
- [Understanding intermediate layers using linear classifier probes](https://mlsanity.com/paper/1610.01644/) (2016)
- [BitFit: Simple Parameter-efficient Fine-tuning for Transformer-based Masked Language-models](https://mlsanity.com/paper/2106.10199/) (2021)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Remote Sensing Image Scene Classification: Benchmark and State of the Art](https://mlsanity.com/paper/1703.00121/) (2017)
- [AdaptFormer: Adapting Vision Transformers for Scalable Visual Recognition](https://mlsanity.com/paper/2205.13535/) (2022)
- [P-Tuning v2: Prompt Tuning Can Be Comparable to Fine-tuning Universally Across Scales and Tasks](https://mlsanity.com/paper/2110.07602/) (2021)
- [DynamiCrafter: Animating Open-domain Images with Video Diffusion Priors](https://mlsanity.com/paper/2310.12190/) (2023)
- [A Large-scale Study of Representation Learning with the Visual Task Adaptation Benchmark](https://mlsanity.com/paper/1910.04867/) (2019)
- [LoRA Learns Less and Forgets Less](https://mlsanity.com/paper/2405.09673/) (2024)
- [Scaling & Shifting Your Features: A New Baseline for Efficient Model Tuning](https://mlsanity.com/paper/2210.08823/) (2022)
- [The Carbon Footprint of Machine Learning Training Will Plateau, Then Shrink](https://mlsanity.com/paper/2204.05149/) (2022)

## Abstract (arXiv)

Advances in Parameter-Efficient Fine-Tuning (PEFT) bridged the performance gap with Full Fine-Tuning (FFT) through sophisticated analysis of pre-trained parameter spaces. Starting from drawing insights from Neural Engrams (NE) in Biological Neural Networks (BNNs), we establish a connection between the low-rank property observed during PEFT's parameter space shifting and neurobiological mechanisms. This observation leads to our proposed method, Synapse and Neuron (SAN), which decomposes and propagates scaling components from anterior feature adjusting vectors towards posterior weight matrices. Our approach is theoretically grounded in Long-Term Potentiation/Depression (LTP/D) phenomena, which govern synapse development through neurotransmitter release modulation. Extensive experiments demonstrate its effectiveness: on vision tasks across VTAB, FGVC, and GIC (25 datasets) using ViT, SwinT and ConvNeXt, SAN outperforms FFT up to 8.7% and LoRA by 3.2%; on language tasks using Commonsense Reasoning (8 datasets) with LLaMA models (all generations), surpassing ChatGPT up to 8.5% and LoRA by 4.7%; on visual-language tasks using Mixed Visual Instruction (7 datasets) with LLaVA models, it exceeds FFT up to 2.4% and LoRA by 1.9%. Our code and W&B log will be released.