# Deep Self-Cleansing for Medical Image Segmentation with Noisy Labels

arXiv: https://arxiv.org/abs/2409.05024 · HTML: https://mlsanity.com/paper/2409.05024/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 50 references that are in the map.
- First posted on arXiv 8 Sep 2024.

## Builds on (most cited first, 30 of 30)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Generalized Cross Entropy Loss for Training Deep Neural Networks with Noisy Labels](https://mlsanity.com/paper/1805.07836/) (2018)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [A Closer Look at Memorization in Deep Networks](https://mlsanity.com/paper/1706.05394/) (2017)
- [DivideMix: Learning with Noisy Labels as Semi-supervised Learning](https://mlsanity.com/paper/2002.07394/) (2020)
- [Learning to Reweight Examples for Robust Deep Learning](https://mlsanity.com/paper/1803.09050/) (2018)
- [Robust Loss Functions under Label Noise for Deep Neural Networks](https://mlsanity.com/paper/1712.09482/) (2017)
- [Confident Learning: Estimating Uncertainty in Dataset Labels](https://mlsanity.com/paper/1911.00068/) (2019)
- [UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentation](https://mlsanity.com/paper/2004.08790/) (2020)
- [Joint Optimization Framework for Learning with Noisy Labels](https://mlsanity.com/paper/1803.11364/) (2018)
- [Combating noisy labels by agreement: A joint training method with co-regularization](https://mlsanity.com/paper/2003.02752/) (2020)
- [ResUNet-a: a deep learning framework for semantic segmentation of remotely sensed data](https://mlsanity.com/paper/1904.00592/) (2019)
- [Probabilistic End-to-end Noise Correction for Learning with Noisy Labels](https://mlsanity.com/paper/1903.07788/) (2019)
- [Understanding and Utilizing Deep Neural Networks Trained with Noisy Labels](https://mlsanity.com/paper/1905.05040/) (2019)
- [Learning with Instance-Dependent Label Noise: A Sample Sieve Approach](https://mlsanity.com/paper/2010.02347/) (2020)
- [DS-TransUNet:Dual Swin Transformer U-Net for Medical Image Segmentation](https://mlsanity.com/paper/2106.06716/) (2021)
- [Deep Self-Learning From Noisy Labels](https://mlsanity.com/paper/1908.02160/) (2019)
- [Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistency](https://mlsanity.com/paper/2012.07042/) (2020)
- [Error-Bounded Correction of Noisy Labels](https://mlsanity.com/paper/2011.10077/) (2020)
- [Modified U-Net (mU-Net) with Incorporation of Object-Dependent High Level Features for Improved Liver and Liver-Tumor Segmentation in CT Images](https://mlsanity.com/paper/1911.00140/) (2019)
- [Pick-and-Learn: Automatic Quality Evaluation for Noisy-Labeled Image Segmentation](https://mlsanity.com/paper/1907.11835/) (2019)
- [Superpixel-guided Iterative Learning from Noisy Labels for Medical Image Segmentation](https://mlsanity.com/paper/2107.10100/) (2021)
- [Noisy Labels are Treasure: Mean-Teacher-Assisted Confident Learning for Hepatic Vessel Segmentation](https://mlsanity.com/paper/2106.01860/) (2021)

## Built on by (most cited first, 2 of 2)

- [Evaluating Interactive 2D Visualization as a Sample Selection Strategy for Biomedical Time-Series Data Annotation](https://mlsanity.com/paper/2603.26592/) (2026)
- [Decoupled Single-Mask Annotation Noise Detection via Cross-Sectional Patch Self-Consistency](https://mlsanity.com/paper/2607.05965/) (2026)

## Abstract (arXiv)

Medical image segmentation is crucial in the field of medical imaging, aiding in disease diagnosis and surgical planning. Most established segmentation methods rely on supervised deep learning, in which clean and precise labels are essential for supervision and significantly impact the performance of models. However, manually delineated labels often contain noise, such as missing labels and inaccurate boundary delineation, which can hinder networks from correctly modeling target characteristics. In this paper, we propose a deep self-cleansing segmentation framework that can preserve clean labels while cleansing noisy ones in the training phase. To achieve this, we devise a gaussian mixture model-based label filtering module that distinguishes noisy labels from clean labels. Additionally, we develop a label cleansing module to generate pseudo low-noise labels for identified noisy samples. The preserved clean labels and pseudo-labels are then used jointly to supervise the network. Validated on a clinical liver tumor dataset and a public cardiac diagnosis dataset, our method can effectively suppress the interference from noisy labels and achieve prominent segmentation performance.