# Instruction-tuned Large Language Models for Machine Translation in the Medical Domain

arXiv: https://arxiv.org/abs/2408.16440 · HTML: https://mlsanity.com/paper/2408.16440/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 40 references that are in the map.
- First posted on arXiv 29 Aug 2024.

## Builds on (most cited first, 14 of 14)

- [The Llama 3 Herd of Models](https://mlsanity.com/paper/2407.21783/) (2024)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [COMET: A Neural Framework for MT Evaluation](https://mlsanity.com/paper/2009.09025/) (2020)
- [Quantifying the Carbon Emissions of Machine Learning](https://mlsanity.com/paper/1910.09700/) (2019)
- [xCOMET: Transparent Machine Translation Evaluation through Fine-grained Error Detection](https://mlsanity.com/paper/2310.10482/) (2023)
- [Tower: An Open Multilingual Large Language Model for Translation-Related Tasks](https://mlsanity.com/paper/2402.17733/) (2024)
- [Scaling up COMETKIWI: Unbabel-IST 2023 Submission for the Quality Estimation Shared Task](https://mlsanity.com/paper/2309.11925/) (2023)
- [Investigating the Translation Performance of a Large Multilingual Language Model: the Case of BLOOM](https://mlsanity.com/paper/2303.01911/) (2023)
- [Steering Large Language Models for Machine Translation with Finetuning and In-Context Learning](https://mlsanity.com/paper/2310.13448/) (2023)
- [Fine-tuning Large Language Models for Domain-specific Machine Translation](https://mlsanity.com/paper/2402.15061/) (2024)
- [Machine Translation with Large Language Models: Prompt Engineering for Persian, English, and Russian Directions](https://mlsanity.com/paper/2401.08429/) (2024)
- [Domain Adaptive Inference for Neural Machine Translation](https://mlsanity.com/paper/1906.00408/) (2019)

## Built on by (most cited first, 4 of 4)

- [Translation Analytics for Freelancers: I. Introduction, Data Preparation, Baseline Evaluations](https://mlsanity.com/paper/2504.14619/) (2025)
- [Comparing Large Language Models and Traditional Machine Translation Tools for Translating Medical Consultation Summaries: A Pilot Study](https://mlsanity.com/paper/2504.16601/) (2025)
- [On Temperature-Constrained Non-Deterministic Machine Translation: Potential and Evaluation](https://mlsanity.com/paper/2601.13729/) (2026)
- [Translation Analytics for Freelancers II: Benchmarking Local LLMs for Confidential Translation Workflows](https://mlsanity.com/paper/2605.31452/) (2026)

## Abstract (arXiv)

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural machine translation models. The consistency in the machine translation of terminology is crucial for users, researchers, and translators in specialised domains. In this study, we compare the performance between baseline LLMs and instruction-tuned LLMs in the medical domain. In addition, we introduce terminology from specialised medical dictionaries into the instruction formatted datasets for fine-tuning LLMs. The instruction-tuned LLMs significantly outperform the baseline models with automatic metrics.
