# Reconstruct Spine CT from Biplanar X-Rays via Diffusion Learning

arXiv: https://arxiv.org/abs/2408.09731 · HTML: https://mlsanity.com/paper/2408.09731/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 15 references that are in the map.
- First posted on arXiv 19 Aug 2024.

## Builds on (most cited first, 9 of 9)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [Image Super-Resolution via Iterative Refinement](https://mlsanity.com/paper/2104.07636/) (2021)
- [ILVR: Conditioning Method for Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2108.02938/) (2021)
- [X2CT-GAN: Reconstructing CT from Biplanar X-Rays with Generative Adversarial Networks](https://mlsanity.com/paper/1905.06902/) (2019)
- [End-To-End Convolutional Neural Network for 3D Reconstruction of Knee Bones From Bi-Planar X-Ray Images](https://mlsanity.com/paper/2004.00871/) (2020)

## Abstract (arXiv)

Intraoperative CT imaging serves as a crucial resource for surgical guidance; however, it may not always be readily accessible or practical to implement. In scenarios where CT imaging is not an option, reconstructing CT scans from X-rays can offer a viable alternative. In this paper, we introduce an innovative method for 3D CT reconstruction utilizing biplanar X-rays. Distinct from previous research that relies on conventional image generation techniques, our approach leverages a conditional diffusion process to tackle the task of reconstruction. More precisely, we employ a diffusion-based probabilistic model trained to produce 3D CT images based on orthogonal biplanar X-rays. To improve the structural integrity of the reconstructed images, we incorporate a novel projection loss function. Experimental results validate that our proposed method surpasses existing state-of-the-art benchmarks in both visual image quality and multiple evaluative metrics. Specifically, our technique achieves a higher Structural Similarity Index (SSIM) of 0.83, a relative increase of 10%, and a lower Fr'echet Inception Distance (FID) of 83.43, which represents a relative decrease of 25%.