# Predicting Lung Cancer Patient Prognosis with Large Language Models

arXiv: https://arxiv.org/abs/2408.07971 · HTML: https://mlsanity.com/paper/2408.07971/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 6 of its 37 references that are in the map.
- First posted on arXiv 15 Aug 2024.

## Builds on (most cited first, 6 of 6)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [Multimodal ChatGPT for Medical Applications: an Experimental Study of GPT-4V](https://mlsanity.com/paper/2310.19061/) (2023)
- [Prompting Large Language Models for Zero-Shot Clinical Prediction with Structured Longitudinal Electronic Health Record Data](https://mlsanity.com/paper/2402.01713/) (2024)
- [The current status of large language models in summarizing radiology report impressions](https://mlsanity.com/paper/2406.02134/) (2024)

## Built on by (most cited first, 1 of 1)

- [Tabular Foundation Models Can Do Survival Analysis](https://mlsanity.com/paper/2601.22259/) (2026)

## Abstract (arXiv)

Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained attention for their ability to process and generate text based on extensive learned knowledge. In this study, we evaluate the potential of GPT-4o mini and GPT-3.5 in predicting the prognosis of lung cancer patients. We collected two prognosis datasets, i.e., survival and post-operative complication datasets, and designed multiple tasks to assess the models' performance comprehensively. Logistic regression models were also developed as baselines for comparison. The experimental results demonstrate that LLMs can achieve competitive, and in some tasks superior, performance in lung cancer prognosis prediction compared to data-driven logistic regression models despite not using additional patient data. These findings suggest that LLMs can be effective tools for prognosis prediction in lung cancer, particularly when patient data is limited or unavailable.