# Weakly Supervised Intracranial Hemorrhage Segmentation with YOLO and an Uncertainty Rectified Segment Anything Model

arXiv: https://arxiv.org/abs/2407.20461 · HTML: https://mlsanity.com/paper/2407.20461/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 10 of its 25 references that are in the map.
- First posted on arXiv 29 Jul 2024.

## Builds on (most cited first, 10 of 10)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [A Comprehensive Review of YOLO Architectures in Computer Vision: From YOLOv1 to YOLOv8 and YOLO-NAS](https://mlsanity.com/paper/2304.00501/) (2023)
- [Intracranial Hemorrhage Segmentation Using Deep Convolutional Model](https://mlsanity.com/paper/1910.08643/) (2019)
- [Cost-Sensitive Active Learning for Intracranial Hemorrhage Detection](https://mlsanity.com/paper/1809.02882/) (2018)
- [WSI-SAM: Multi-resolution Segment Anything Model (SAM) for histopathology whole-slide images](https://mlsanity.com/paper/2403.09257/) (2024)
- [Weakly Supervised Intracranial Hemorrhage Segmentation using Head-Wise Gradient-Infused Self-Attention Maps from a Swin Transformer in Categorical Learning](https://mlsanity.com/paper/2304.04902/) (2023)
- [Weakly supervised deep learning-based intracranial hemorrhage localization](https://mlsanity.com/paper/2105.00781/) (2021)

## Built on by (most cited first, 3 of 3)

- [TextSAM-EUS: Text Prompt Learning for SAM to Accurately Segment Pancreatic Tumor in Endoscopic Ultrasound](https://mlsanity.com/paper/2507.18082/) (2025)
- [Federated Voxel Scene Graph for Intracranial Hemorrhage](https://mlsanity.com/paper/2411.00578/) (2024)
- [SWDL: Stratum-Wise Difference Learning with Deep Laplacian Pyramid for Semi-Supervised 3D Intracranial Hemorrhage Segmentation](https://mlsanity.com/paper/2506.10325/) (2025)

## Abstract (arXiv)

Intracranial hemorrhage (ICH) is a life-threatening condition that requires rapid and accurate diagnosis to improve treatment outcomes and patient survival rates. Recent advancements in supervised deep learning have greatly improved the analysis of medical images, but often rely on extensive datasets with high-quality annotations, which are costly, time-consuming, and require medical expertise to prepare. To mitigate the need for large amounts of expert-prepared segmentation data, we have developed a novel weakly supervised ICH segmentation method that utilizes the YOLO object detection model and an uncertainty-rectified Segment Anything Model (SAM). In addition, we have proposed a novel point prompt generator for this model to further improve segmentation results with YOLO-predicted bounding box prompts. Our approach achieved a high accuracy of 0.933 and an AUC of 0.796 in ICH detection, along with a mean Dice score of 0.629 for ICH segmentation, outperforming existing weakly supervised and popular supervised (UNet and Swin-UNETR) approaches. Overall, the proposed method provides a robust and accurate alternative to the more commonly used supervised techniques for ICH quantification without requiring refined segmentation ground truths during model training.
