# Leveraging Bi-Focal Perspectives and Granular Feature Integration for Accurate Reliable Early Alzheimer's Detection

arXiv: https://arxiv.org/abs/2407.10921 · HTML: https://mlsanity.com/paper/2407.10921/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 37 references that are in the map.
- First posted on arXiv 15 Jul 2024.

## Builds on (most cited first, 13 of 13)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Inception-v4, Inception-ResNet and the Impact of Residual Connections on Learning](https://mlsanity.com/paper/1602.07261/) (2016)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [Deep Learning in Alzheimer's disease: Diagnostic Classification and Prognostic Prediction using Neuroimaging Data](https://mlsanity.com/paper/1905.00931/) (2019)
- [Automatic Assessment of Alzheimer's Disease Diagnosis Based on Deep Learning Techniques](https://mlsanity.com/paper/2105.08446/) (2021)

## Built on by (most cited first, 1 of 1)

- [Targeted Neural Architectures in Multi-Objective Frameworks for Complete Glioma Characterization from Multimodal MRI](https://mlsanity.com/paper/2409.17273/) (2024)

## Abstract (arXiv)

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a challenging task. Traditional CNNs can extract a good amount of low-level information in an image while failing to extract high-level minuscule particles, which is a significant challenge in detecting AD from MRI scans. To overcome this, we propose a novel Granular Feature Integration method to combine information extraction at different scales along with an efficient information flow, enabling the model to capture both broad and fine-grained features simultaneously. We also propose a Bi-Focal Perspective mechanism to highlight the subtle neurofibrillary tangles and amyloid plaques in the MRI scans, ensuring that critical pathological markers are accurately identified. Our model achieved an F1-Score of 99.31%, precision of 99.24%, and recall of 99.51%. These scores prove that our model is significantly better than the state-of-the-art (SOTA) CNNs in existence.