# DALL-M: Context-Aware Clinical Data Augmentation with LLMs

arXiv: https://arxiv.org/abs/2407.08227 · HTML: https://mlsanity.com/paper/2407.08227/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 50 of its 106 references that are in the map.
- First posted on arXiv 11 Jul 2024.

## Builds on (most cited first, 30 of 50)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Revisiting Deep Learning Models for Tabular Data](https://mlsanity.com/paper/2106.11959/) (2021)
- [Modeling Tabular data using Conditional GAN](https://mlsanity.com/paper/1907.00503/) (2019)
- [TabNet: Attentive Interpretable Tabular Learning](https://mlsanity.com/paper/1908.07442/) (2019)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [Zephyr: Direct Distillation of LM Alignment](https://mlsanity.com/paper/2310.16944/) (2023)
- [ClinicalBERT: Modeling Clinical Notes and Predicting Hospital Readmission](https://mlsanity.com/paper/1904.05342/) (2019)
- [Language Models are Realistic Tabular Data Generators](https://mlsanity.com/paper/2210.06280/) (2022)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [GatorTron: A Large Clinical Language Model to Unlock Patient Information from Unstructured Electronic Health Records](https://mlsanity.com/paper/2203.03540/) (2022)
- [Data Synthesis based on Generative Adversarial Networks](https://mlsanity.com/paper/1806.03384/) (2018)
- [A Study of Generative Large Language Model for Medical Research and Healthcare](https://mlsanity.com/paper/2305.13523/) (2023)
- [Large Language Models(LLMs) on Tabular Data: Prediction, Generation, and Understanding -- A Survey](https://mlsanity.com/paper/2402.17944/) (2024)
- [SCARF: Self-Supervised Contrastive Learning using Random Feature Corruption](https://mlsanity.com/paper/2106.15147/) (2021)
- [Handling Incomplete Heterogeneous Data using VAEs](https://mlsanity.com/paper/1807.03653/) (2018)
- [TransTab: Learning Transferable Tabular Transformers Across Tables](https://mlsanity.com/paper/2205.09328/) (2022)
- [On Protecting the Data Privacy of Large Language Models (LLMs): A Survey](https://mlsanity.com/paper/2403.05156/) (2024)
- [HuatuoGPT-II, One-stage Training for Medical Adaption of LLMs](https://mlsanity.com/paper/2311.09774/) (2023)
- [Benchmarking Large Language Models on CMExam -- A Comprehensive Chinese Medical Exam Dataset](https://mlsanity.com/paper/2306.03030/) (2023)
- [ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluation](https://mlsanity.com/paper/2306.09968/) (2023)
- [Conditional Wasserstein GAN-based Oversampling of Tabular Data for Imbalanced Learning](https://mlsanity.com/paper/2008.09202/) (2020)
- [ChiMed-GPT: A Chinese Medical Large Language Model with Full Training Regime and Better Alignment to Human Preferences](https://mlsanity.com/paper/2311.06025/) (2023)

## Built on by (most cited first, 2 of 2)

- [A Structured Review of Underwater Object Detection Challenges and Solutions: From Traditional to Large Vision Language Models](https://mlsanity.com/paper/2509.08490/) (2025)
- [LLM-Assisted Emergency Triage Benchmark: Bridging Hospital-Rich and MCI-Like Field Simulation](https://mlsanity.com/paper/2509.26351/) (2025)

## Abstract (arXiv)

X-ray images are vital in medical diagnostics, but their effectiveness is limited without clinical context. Radiologists often find chest X-rays insufficient for diagnosing underlying diseases, necessitating the integration of structured clinical features with radiology reports. To address this, we introduce DALL-M, a novel framework that enhances clinical datasets by generating contextual synthetic data. DALL-M augments structured patient data, including vital signs (e.g., heart rate, oxygen saturation), radiology findings (e.g., lesion presence), and demographic factors. It integrates this tabular data with contextual knowledge extracted from radiology reports and domain-specific resources (e.g., Radiopaedia, Wikipedia), ensuring clinical consistency and reliability. DALL-M follows a three-phase process: (i) clinical context storage, (ii) expert query generation, and (iii) context-aware feature augmentation. Using large language models (LLMs), it generates both contextual synthetic values for existing clinical features and entirely new, clinically relevant features. Applied to 799 cases from the MIMIC-IV dataset, DALL-M expanded the original 9 clinical features to 91. Empirical validation with machine learning models (including Decision Trees, Random Forests, XGBoost, and TabNET) demonstrated a 16.5% improvement in F1 score and a 25% increase in Precision and Recall. DALL-M bridges an important gap in clinical data augmentation by preserving data integrity while enhancing predictive modeling in healthcare. Our results show that integrating LLM-generated synthetic features significantly improves model performance, making DALL-M a scalable and practical approach for AI-driven medical diagnostics.