# HDKD: Hybrid Data-Efficient Knowledge Distillation Network for Medical Image Classification

arXiv: https://arxiv.org/abs/2407.07516 · HTML: https://mlsanity.com/paper/2407.07516/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Placed in General knowledge distillation methods, one of 12 directions in Knowledge distillation.
- Builds on 56 of its 69 references that are in the map.
- First posted on arXiv 10 Jul 2024.

## Placed in

- Knowledge distillation / [General knowledge distillation methods](https://mlsanity.com/distill/general-knowledge-distillation-methods/)

## Builds on (most cited first, 30 of 56)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Layer Normalization](https://mlsanity.com/paper/1607.06450/) (2016)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [Gaussian Error Linear Units (GELUs)](https://mlsanity.com/paper/1606.08415/) (2016)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Searching for MobileNetV3](https://mlsanity.com/paper/1905.02244/) (2019)
- [Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutions](https://mlsanity.com/paper/2102.12122/) (2021)
- [Knowledge Distillation: A Survey](https://mlsanity.com/paper/2006.05525/) (2020)
- [Swin Transformer V2: Scaling Up Capacity and Resolution](https://mlsanity.com/paper/2111.09883/) (2021)
- [ShuffleNet: An Extremely Efficient Convolutional Neural Network for Mobile Devices](https://mlsanity.com/paper/1707.01083/) (2017)
- [A Comprehensive Survey on Transfer Learning](https://mlsanity.com/paper/1911.02685/) (2019)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [Designing Network Design Spaces](https://mlsanity.com/paper/2003.13678/) (2020)
- [MnasNet: Platform-Aware Neural Architecture Search for Mobile](https://mlsanity.com/paper/1807.11626/) (2018)
- [Revisiting Unreasonable Effectiveness of Data in Deep Learning Era](https://mlsanity.com/paper/1707.02968/) (2017)
- [Relational Knowledge Distillation](https://mlsanity.com/paper/1904.05068/) (2019)
- [CrossViT: Cross-Attention Multi-Scale Vision Transformer for Image Classification](https://mlsanity.com/paper/2103.14899/) (2021)
- [PVT v2: Improved Baselines with Pyramid Vision Transformer](https://mlsanity.com/paper/2106.13797/) (2021)

## Built on by (most cited first, 3 of 3)

- [Dynamic Weight Adjustment for Knowledge Distillation: Leveraging Vision Transformer for High-Accuracy Lung Cancer Detection and Real-Time Deployment](https://mlsanity.com/paper/2510.20438/) (2025)
- [WeCKD: Weakly-supervised Chained Distillation Network for Efficient Multimodal Medical Imaging](https://mlsanity.com/paper/2510.14668/) (2025)
- [CD-FKD: Cross-Domain Feature Knowledge Distillation for Robust Single-Domain Generalization in Object Detection](https://mlsanity.com/paper/2603.16439/) (2026)

## Abstract (arXiv)

Vision Transformers (ViTs) have achieved significant advancement in computer vision tasks due to their powerful modeling capacity. However, their performance notably degrades when trained with insufficient data due to lack of inherent inductive biases. Distilling knowledge and inductive biases from a Convolutional Neural Network (CNN) teacher has emerged as an effective strategy for enhancing the generalization of ViTs on limited datasets. Previous approaches to Knowledge Distillation (KD) have pursued two primary paths: some focused solely on distilling the logit distribution from CNN teacher to ViT student, neglecting the rich semantic information present in intermediate features due to the structural differences between them. Others integrated feature distillation along with logit distillation, yet this introduced alignment operations that limits the amount of knowledge transferred due to mismatched architectures and increased the computational overhead. To this end, this paper presents Hybrid Data-efficient Knowledge Distillation (HDKD) paradigm which employs a CNN teacher and a hybrid student. The choice of hybrid student serves two main aspects. First, it leverages the strengths of both convolutions and transformers while sharing the convolutional structure with the teacher model. Second, this shared structure enables the direct application of feature distillation without any information loss or additional computational overhead. Additionally, we propose an efficient light-weight convolutional block named Mobile Channel-Spatial Attention (MBCSA), which serves as the primary convolutional block in both teacher and student models. Extensive experiments on two medical public datasets showcase the superiority of HDKD over other state-of-the-art models and its computational efficiency. Source code at: https://github.com/omarsherif200/HDKD