# D-MASTER: Mask Annealed Transformer for Unsupervised Domain Adaptation in Breast Cancer Detection from Mammograms

arXiv: https://arxiv.org/abs/2407.06585 · HTML: https://mlsanity.com/paper/2407.06585/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 44 references that are in the map.
- First posted on arXiv 9 Jul 2024.

## Builds on (most cited first, 29 of 29)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [SGDR: Stochastic Gradient Descent with Warm Restarts](https://mlsanity.com/paper/1608.03983/) (2016)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [Deformable DETR: Deformable Transformers for End-to-End Object Detection](https://mlsanity.com/paper/2010.04159/) (2020)
- [VideoMAE: Masked Autoencoders are Data-Efficient Learners for Self-Supervised Video Pre-Training](https://mlsanity.com/paper/2203.12602/) (2022)
- [DINO: DETR with Improved DeNoising Anchor Boxes for End-to-End Object Detection](https://mlsanity.com/paper/2203.03605/) (2022)
- [YOLOX: Exceeding YOLO Series in 2021](https://mlsanity.com/paper/2107.08430/) (2021)
- [DAB-DETR: Dynamic Anchor Boxes are Better Queries for DETR](https://mlsanity.com/paper/2201.12329/) (2022)
- [DN-DETR: Accelerate DETR Training by Introducing Query DeNoising](https://mlsanity.com/paper/2203.01305/) (2022)
- [Domain Adaptive Faster R-CNN for Object Detection in the Wild](https://mlsanity.com/paper/1803.03243/) (2018)
- [Driving in the Matrix: Can Virtual Worlds Replace Human-Generated Annotations for Real World Tasks?](https://mlsanity.com/paper/1610.01983/) (2016)
- [Focal Modulation Networks](https://mlsanity.com/paper/2203.11926/) (2022)
- [Unbiased Mean Teacher for Cross-domain Object Detection](https://mlsanity.com/paper/2003.00707/) (2020)
- [Cross-Domain Adaptive Teacher for Object Detection](https://mlsanity.com/paper/2111.13216/) (2021)
- [MeGA-CDA: Memory Guided Attention for Category-Aware Unsupervised Domain Adaptive Object Detection](https://mlsanity.com/paper/2103.04224/) (2021)
- [CLIP the Gap: A Single Domain Generalization Approach for Object Detection](https://mlsanity.com/paper/2301.05499/) (2023)
- [SIGMA: Semantic-complete Graph Matching for Domain Adaptive Object Detection](https://mlsanity.com/paper/2203.06398/) (2022)
- [Learning Domain Adaptive Object Detection with Probabilistic Teacher](https://mlsanity.com/paper/2206.06293/) (2022)
- [Exploring Sequence Feature Alignment for Domain Adaptive Detection Transformers](https://mlsanity.com/paper/2107.12636/) (2021)
- [Seeking Similarities over Differences: Similarity-based Domain Alignment for Adaptive Object Detection](https://mlsanity.com/paper/2110.01428/) (2021)
- [Decoupled Adaptation for Cross-Domain Object Detection](https://mlsanity.com/paper/2110.02578/) (2021)
- [MTTrans: Cross-Domain Object Detection with Mean-Teacher Transformer](https://mlsanity.com/paper/2205.01643/) (2022)
- [ConfMix: Unsupervised Domain Adaptation for Object Detection via Confidence-based Mixing](https://mlsanity.com/paper/2210.11539/) (2022)
- [DA-DETR: Domain Adaptive Detection Transformer with Information Fusion](https://mlsanity.com/paper/2103.17084/) (2021)
- [Synergizing between Self-Training and Adversarial Learning for Domain Adaptive Object Detection](https://mlsanity.com/paper/2110.00249/) (2021)
- [Robust T-Loss for Medical Image Segmentation](https://mlsanity.com/paper/2306.00753/) (2023)
- [Deep Learning-based Facial Appearance Simulation Driven by Surgically Planned Craniomaxillofacial Bony Movement](https://mlsanity.com/paper/2210.01685/) (2022)

## Built on by (most cited first, 4 of 4)

- [CarePilot: A Multi-Agent Framework for Long-Horizon Computer Task Automation in Healthcare](https://mlsanity.com/paper/2603.24157/) (2026)
- [MedSPOT: A Workflow-Aware Sequential Grounding Benchmark for Clinical GUI](https://mlsanity.com/paper/2603.19993/) (2026)
- [Context Aware Grounded Teacher for Source Free Object Detection](https://mlsanity.com/paper/2504.15404/) (2025)
- [Analysis of Invasive Breast Cancer in Mammograms Using YOLO, Explainability, and Domain Adaptation](https://mlsanity.com/paper/2512.00129/) (2025)

## Abstract (arXiv)

We focus on the problem of Unsupervised Domain Adaptation (uda) for breast cancer detection from mammograms (BCDM) problem. Recent advancements have shown that masked image modeling serves as a robust pretext task for UDA. However, when applied to cross-domain BCDM, these techniques struggle with breast abnormalities such as masses, asymmetries, and micro-calcifications, in part due to the typically much smaller size of region of interest in comparison to natural images. This often results in more false positives per image (FPI) and significant noise in pseudo-labels typically used to bootstrap such techniques. Recognizing these challenges, we introduce a transformer-based Domain-invariant Mask Annealed Student Teacher autoencoder (D-MASTER) framework. D-MASTER adaptively masks and reconstructs multi-scale feature maps, enhancing the model's ability to capture reliable target domain features. D-MASTER also includes adaptive confidence refinement to filter pseudo-labels, ensuring only high-quality detections are considered. We also provide a bounding box annotated subset of 1000 mammograms from the RSNA Breast Screening Dataset (referred to as RSNA-BSD1K) to support further research in BCDM. We evaluate D-MASTER on multiple BCDM datasets acquired from diverse domains. Experimental results show a significant improvement of 9% and 13% in sensitivity at 0.3 FPI over state-of-the-art UDA techniques on publicly available benchmark INBreast and DDSM datasets respectively. We also report an improvement of 11% and 17% on In-house and RSNA-BSD1K datasets respectively. The source code, pre-trained D-MASTER model, along with RSNA-BSD1K dataset annotations is available at https://dmaster-iitd.github.io/webpage.
