# Accelerated Proton Resonance Frequency-based Magnetic Resonance Thermometry by Optimized Deep Learning Method

arXiv: https://arxiv.org/abs/2407.03308 · HTML: https://mlsanity.com/paper/2407.03308/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 19 of its 53 references that are in the map.
- First posted on arXiv 3 Jul 2024.

## Builds on (most cited first, 19 of 19)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Distilling the Knowledge in a Neural Network](https://mlsanity.com/paper/1503.02531/) (2015)
- [fastMRI: An Open Dataset and Benchmarks for Accelerated MRI](https://mlsanity.com/paper/1811.08839/) (2018)
- [Effective Data Augmentation With Diffusion Models](https://mlsanity.com/paper/2302.07944/) (2023)
- [A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction](https://mlsanity.com/paper/1704.02422/) (2017)
- [U-Net and its variants for medical image segmentation: theory and applications](https://mlsanity.com/paper/2011.01118/) (2020)
- [A Deep Cascade of Convolutional Neural Networks for MR Image Reconstruction](https://mlsanity.com/paper/1703.00555/) (2017)
- [Swin Transformer for Fast MRI](https://mlsanity.com/paper/2201.03230/) (2022)
- [Deep Residual Learning for Accelerated MRI using Magnitude and Phase Networks](https://mlsanity.com/paper/1804.00432/) (2018)
- [ReconFormer: Accelerated MRI Reconstruction Using Recurrent Transformer](https://mlsanity.com/paper/2201.09376/) (2022)
- [Deep Learning Approaches for Data Augmentation in Medical Imaging: A Review](https://mlsanity.com/paper/2307.13125/) (2023)
- [A review and experimental evaluation of deep learning methods for MRI reconstruction](https://mlsanity.com/paper/2109.08618/) (2021)
- [Complex Fully Convolutional Neural Networks for MR Image Reconstruction](https://mlsanity.com/paper/1807.03343/) (2018)
- [KD-MRI: A knowledge distillation framework for image reconstruction and image restoration in MRI workflow](https://mlsanity.com/paper/2004.05319/) (2020)
- [Deep Residual Dense U-Net for Resolution Enhancement in Accelerated MRI Acquisition](https://mlsanity.com/paper/2001.04488/) (2020)
- [Multi-branch Cascaded Swin Transformers with Attention to k-space Sampling Pattern for Accelerated MRI Reconstruction](https://mlsanity.com/paper/2207.08412/) (2022)

## Abstract (arXiv)

Proton resonance frequency (PRF) based MR thermometry is essential for focused ultrasound (FUS) thermal ablation therapies. This work aims to enhance temporal resolution in dynamic MR temperature map reconstruction using an improved deep learning method. The training-optimized methods and five classical neural networks were applied on the 2-fold and 4-fold under-sampling k-space data to reconstruct the temperature maps. The enhanced training modules included offline/online data augmentations, knowledge distillation, and the amplitude-phase decoupling loss function. The heating experiments were performed by a FUS transducer on phantom and ex vivo tissues, respectively. These data were manually under-sampled to imitate acceleration procedures and trained in our method to get the reconstruction model. The additional dozen or so testing datasets were separately obtained for evaluating the real-time performance and temperature accuracy. Acceleration factors of 1.9 and 3.7 were found for 2 times and 4 times k-space under-sampling strategies and the ResUNet-based deep learning reconstruction performed exceptionally well. In 2-fold acceleration scenario, the RMSE of temperature map patches provided the values of 0.888 degree centigrade and 1.145 degree centigrade on phantom and ex vivo testing datasets. The DICE value of temperature areas enclosed by 43 degree centigrade isotherm was 0.809, and the Bland-Altman analysis showed a bias of -0.253 degree centigrade with the apart of plus or minus 2.16 degree centigrade. In 4 times under-sampling case, these evaluating values decreased by approximately 10%. This study demonstrates that deep learning-based reconstruction can significantly enhance the accuracy and efficiency of MR thermometry for clinical FUS thermal therapies.