# Individual brain parcellation: Review of methods, validations and applications

arXiv: https://arxiv.org/abs/2407.00984 · HTML: https://mlsanity.com/paper/2407.00984/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 2 of its 107 references that are in the map.
- First posted on arXiv 1 Jul 2024.

## Builds on (most cited first, 2 of 2)

- [SwiFT: Swin 4D fMRI Transformer](https://mlsanity.com/paper/2307.05916/) (2023)
- [Brain Age Prediction Based on Resting-State Functional Connectivity Patterns Using Convolutional Neural Networks](https://mlsanity.com/paper/1801.04013/) (2018)

## Built on by (most cited first, 2 of 2)

- [Refined Causal Graph Structure Learning via Curvature for Brain Disease Classification](https://mlsanity.com/paper/2506.15708/) (2025)
- [Atlas-free Brain Network Transformer](https://mlsanity.com/paper/2510.03306/) (2025)

## Abstract (arXiv)

Individual brains vary greatly in morphology, connectivity and organization. The applicability of group-level parcellations is limited by the rapid development of precision medicine today because they do not take into account the variation of parcels at the individual level. Accurate mapping of brain functional regions at the individual level is pivotal for a comprehensive understanding of the variations in brain function and behaviors, early and precise identification of brain abnormalities, as well as personalized treatments for neuropsychiatric disorders. With the development of neuroimaging and machine learning techniques, studies on individual brain parcellation are booming. In this paper, we offer an overview of recent advances in the methodologies of individual brain parcellation, including optimization- and learning-based methods. Comprehensive evaluation metrics to validate individual brain mapping have been introduced. We also review the studies of how individual brain mapping promotes neuroscience research and clinical medicine. Finally, we summarize the major challenges and important future directions of individualized brain parcellation. Collectively, we intend to offer a thorough overview of individual brain parcellation methods, validations, and applications, along with highlighting the current challenges that call for an urgent demand for integrated platforms that integrate datasets, methods, and validations.