# CAT: Coordinating Anatomical-Textual Prompts for Multi-Organ and Tumor Segmentation

arXiv: https://arxiv.org/abs/2406.07085 · HTML: https://mlsanity.com/paper/2406.07085/

## Key facts

- Cited by 14 papers in the map (data through 14 Oct 2026).
- Builds on 48 of its 62 references that are in the map.
- First posted on arXiv 11 Jun 2024.

## Builds on (most cited first, 30 of 48)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Neural Discrete Representation Learning](https://mlsanity.com/paper/1711.00937/) (2017)
- [Grounding DINO: Marrying DINO with Grounded Pre-Training for Open-Set Object Detection](https://mlsanity.com/paper/2303.05499/) (2023)
- [Categorical Reparameterization with Gumbel-Softmax](https://mlsanity.com/paper/1611.01144/) (2016)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [Per-Pixel Classification is Not All You Need for Semantic Segmentation](https://mlsanity.com/paper/2107.06278/) (2021)
- [The Concrete Distribution: A Continuous Relaxation of Discrete Random Variables](https://mlsanity.com/paper/1611.00712/) (2016)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Open-vocabulary Object Detection via Vision and Language Knowledge Distillation](https://mlsanity.com/paper/2104.13921/) (2021)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [Open-Vocabulary Semantic Segmentation with Mask-adapted CLIP](https://mlsanity.com/paper/2210.04150/) (2022)
- [Segment Everything Everywhere All at Once](https://mlsanity.com/paper/2304.06718/) (2023)
- [GroupViT: Semantic Segmentation Emerges from Text Supervision](https://mlsanity.com/paper/2202.11094/) (2022)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [Scaling Open-Vocabulary Image Segmentation with Image-Level Labels](https://mlsanity.com/paper/2112.12143/) (2021)
- [Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysis](https://mlsanity.com/paper/2111.14791/) (2021)
- [Open-Vocabulary Panoptic Segmentation with Text-to-Image Diffusion Models](https://mlsanity.com/paper/2303.04803/) (2023)
- [MaX-DeepLab: End-to-End Panoptic Segmentation with Mask Transformers](https://mlsanity.com/paper/2012.00759/) (2020)
- [AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentation](https://mlsanity.com/paper/2206.08023/) (2022)
- [Mask DINO: Towards A Unified Transformer-based Framework for Object Detection and Segmentation](https://mlsanity.com/paper/2206.02777/) (2022)
- [CHAOS Challenge -- Combined (CT-MR) Healthy Abdominal Organ Segmentation](https://mlsanity.com/paper/2001.06535/) (2020)
- [Customized Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.13785/) (2023)

## Built on by (most cited first, 14 of 14)

- [Med3DVLM: An Efficient Vision-Language Model for 3D Medical Image Analysis](https://mlsanity.com/paper/2503.20047/) (2025)
- [CRISP-SAM2: SAM2 with Cross-Modal Interaction and Semantic Prompting for Multi-Organ Segmentation](https://mlsanity.com/paper/2506.23121/) (2025)
- [BiPVL-Seg: Bidirectional Progressive Vision-Language Fusion with Global-Local Alignment for Medical Image Segmentation](https://mlsanity.com/paper/2503.23534/) (2025)
- [Medal S: Spatio-Textual Prompt Model for Medical Segmentation](https://mlsanity.com/paper/2511.13001/) (2025)
- [Leveraging Textual Anatomical Knowledge for Class-Imbalanced Semi-Supervised Multi-Organ Segmentation](https://mlsanity.com/paper/2501.13470/) (2025)
- [MAST-Pro: Dynamic Mixture-of-Experts for Adaptive Segmentation of Pan-Tumors with Knowledge-Driven Prompts](https://mlsanity.com/paper/2503.14355/) (2025)
- [TK-Mamba: Marrying KAN With Mamba for Text-Driven 3D Medical Image Segmentation](https://mlsanity.com/paper/2505.18525/) (2025)
- [Vision-Language Semantic Aggregation Leveraging Foundation Model for Generalizable Medical Image Segmentation](https://mlsanity.com/paper/2509.08570/) (2025)
- [TGC-Net: A Structure-Aware and Semantically-Aligned Framework for Text-Guided Medical Image Segmentation](https://mlsanity.com/paper/2512.21135/) (2025)
- [Uncertainty-Aware Concept and Motion Segmentation for Semi-Supervised Angiography Videos](https://mlsanity.com/paper/2603.00881/) (2026)
- [ESICA: A Scalable Framework for Text-Guided 3D Medical Image Segmentation](https://mlsanity.com/paper/2604.24876/) (2026)
- [Exploring Prompt Alignment with Clinical Factors in Zero-Shot Segmentation VLMs for NSCLC Tumor Segmentation](https://mlsanity.com/paper/2605.01266/) (2026)
- [UniMedSeg: Unified In-Context Learning for Multi-Paradigm 2D/3D Medical Image Segmentation](https://mlsanity.com/paper/2607.12896/) (2026)
- [MedPlex: Deep Vision-Language Co-Adaptation for Clinically Grounded Medical Segmentation](https://mlsanity.com/paper/2608.13690/) (2026)

## Abstract (arXiv)

Existing promptable segmentation methods in the medical imaging field primarily consider either textual or visual prompts to segment relevant objects, yet they often fall short when addressing anomalies in medical images, like tumors, which may vary greatly in shape, size, and appearance. Recognizing the complexity of medical scenarios and the limitations of textual or visual prompts, we propose a novel dual-prompt schema that leverages the complementary strengths of visual and textual prompts for segmenting various organs and tumors. Specifically, we introduce CAT, an innovative model that Coordinates Anatomical prompts derived from 3D cropped images with Textual prompts enriched by medical domain knowledge. The model architecture adopts a general query-based design, where prompt queries facilitate segmentation queries for mask prediction. To synergize two types of prompts within a unified framework, we implement a ShareRefiner, which refines both segmentation and prompt queries while disentangling the two types of prompts. Trained on a consortium of 10 public CT datasets, CAT demonstrates superior performance in multiple segmentation tasks. Further validation on a specialized in-house dataset reveals the remarkable capacity of segmenting tumors across multiple cancer stages. This approach confirms that coordinating multimodal prompts is a promising avenue for addressing complex scenarios in the medical domain.