# Zero-Shot End-To-End Spoken Question Answering In Medical Domain

arXiv: https://arxiv.org/abs/2406.05876 · HTML: https://mlsanity.com/paper/2406.05876/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 28 of its 33 references that are in the map.
- First posted on arXiv 9 Jun 2024.

## Builds on (most cited first, 28 of 28)

- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Robust Speech Recognition via Large-Scale Weak Supervision](https://mlsanity.com/paper/2212.04356/) (2022)
- [wav2vec 2.0: A Framework for Self-Supervised Learning of Speech Representations](https://mlsanity.com/paper/2006.11477/) (2020)
- [HuBERT: Self-Supervised Speech Representation Learning by Masked Prediction of Hidden Units](https://mlsanity.com/paper/2106.07447/) (2021)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [WavLM: Large-Scale Self-Supervised Pre-Training for Full Stack Speech Processing](https://mlsanity.com/paper/2110.13900/) (2021)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [HiFi-GAN: Generative Adversarial Networks for Efficient and High Fidelity Speech Synthesis](https://mlsanity.com/paper/2010.05646/) (2020)
- [data2vec: A General Framework for Self-supervised Learning in Speech, Vision and Language](https://mlsanity.com/paper/2202.03555/) (2022)
- [Large-scale Contrastive Language-Audio Pretraining with Feature Fusion and Keyword-to-Caption Augmentation](https://mlsanity.com/paper/2211.06687/) (2022)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [Conditional Variational Autoencoder with Adversarial Learning for End-to-End Text-to-Speech](https://mlsanity.com/paper/2106.06103/) (2021)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [SpeechGPT: Empowering Large Language Models with Intrinsic Cross-Modal Conversational Abilities](https://mlsanity.com/paper/2305.11000/) (2023)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [Pengi: An Audio Language Model for Audio Tasks](https://mlsanity.com/paper/2305.11834/) (2023)
- [SpeechT5: Unified-Modal Encoder-Decoder Pre-Training for Spoken Language Processing](https://mlsanity.com/paper/2110.07205/) (2021)
- [PMC-LLaMA: Towards Building Open-source Language Models for Medicine](https://mlsanity.com/paper/2304.14454/) (2023)
- [Clotho-AQA: A Crowdsourced Dataset for Audio Question Answering](https://mlsanity.com/paper/2204.09634/) (2022)
- [Spoken SQuAD: A Study of Mitigating the Impact of Speech Recognition Errors on Listening Comprehension](https://mlsanity.com/paper/1804.00320/) (2018)
- [Multilingual End-to-End Speech Translation](https://mlsanity.com/paper/1910.00254/) (2019)
- [Knowledge Distillation for Improved Accuracy in Spoken Question Answering](https://mlsanity.com/paper/2010.11067/) (2020)
- [Audio-visual Generalised Zero-shot Learning with Cross-modal Attention and Language](https://mlsanity.com/paper/2203.03598/) (2022)
- [Zero-shot Visual Question Answering with Language Model Feedback](https://mlsanity.com/paper/2305.17006/) (2023)
- [Investigating Pre-trained Audio Encoders in the Low-Resource Condition](https://mlsanity.com/paper/2305.17733/) (2023)
- [Mitigating the Impact of Speech Recognition Errors on Spoken Question Answering by Adversarial Domain Adaptation](https://mlsanity.com/paper/1904.07904/) (2019)

## Built on by (most cited first, 2 of 2)

- [SpokenNativQA: Multilingual Everyday Spoken Queries for LLMs](https://mlsanity.com/paper/2505.19163/) (2025)
- [MedSpeak: A Knowledge Graph-Aided ASR Error Correction Framework for Spoken Medical QA](https://mlsanity.com/paper/2602.00981/) (2026)

## Abstract (arXiv)

In the rapidly evolving landscape of spoken question-answering (SQA), the integration of large language models (LLMs) has emerged as a transformative development. Conventional approaches often entail the use of separate models for question audio transcription and answer selection, resulting in significant resource utilization and error accumulation. To tackle these challenges, we explore the effectiveness of end-to-end (E2E) methodologies for SQA in the medical domain. Our study introduces a novel zero-shot SQA approach, compared to traditional cascade systems. Through a comprehensive evaluation conducted on a new open benchmark of 8 medical tasks and 48 hours of synthetic audio, we demonstrate that our approach requires up to 14.7 times fewer resources than a combined 1.3B parameters LLM with a 1.55B parameters ASR model while improving average accuracy by 0.5%. These findings underscore the potential of E2E methodologies for SQA in resource-constrained contexts.