# Vision Mamba: Cutting-Edge Classification of Alzheimer's Disease with 3D MRI Scans

arXiv: https://arxiv.org/abs/2406.05757 · HTML: https://mlsanity.com/paper/2406.05757/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba).
- Builds on 11 of its 19 references that are in the map.
- First posted on arXiv 9 Jun 2024.

## Placed in

- State-space sequence models (S4, Mamba) / [Mamba for medical image analysis](https://mlsanity.com/ssm/mamba-for-medical-image-analysis/)

## Builds on (most cited first, 11 of 11)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Efficiently Modeling Long Sequences with Structured State Spaces](https://mlsanity.com/paper/2111.00396/) (2021)
- [Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Model](https://mlsanity.com/paper/2401.09417/) (2024)
- [Transformers in Vision: A Survey](https://mlsanity.com/paper/2101.01169/) (2021)
- [nnFormer: Interleaved Transformer for Volumetric Segmentation](https://mlsanity.com/paper/2109.03201/) (2021)
- [MambaOut: Do We Really Need Mamba for Vision?](https://mlsanity.com/paper/2405.07992/) (2024)
- [Shunted Self-Attention via Multi-Scale Token Aggregation](https://mlsanity.com/paper/2111.15193/) (2021)
- [Residual and Plain Convolutional Neural Networks for 3D Brain MRI Classification](https://mlsanity.com/paper/1701.06643/) (2017)
- [Visual Mamba: A Survey and New Outlooks](https://mlsanity.com/paper/2404.18861/) (2024)
- [Three-dimensional convolutional neural network (3D-CNN) for heterogeneous material homogenization](https://mlsanity.com/paper/2002.07600/) (2020)

## Built on by (most cited first, 1 of 1)

- [Mamba in Vision: A Comprehensive Survey of Techniques and Applications](https://mlsanity.com/paper/2410.03105/) (2024)

## Abstract (arXiv)

Classifying 3D MRI images for early detection of Alzheimer's disease is a critical task in medical imaging. Traditional approaches using Convolutional Neural Networks (CNNs) and Transformers face significant challenges in this domain. CNNs, while effective in capturing local spatial features, struggle with long-range dependencies and often require extensive computational resources for high-resolution 3D data. Transformers, on the other hand, excel in capturing global context but suffer from quadratic complexity in inference time and require substantial memory, making them less efficient for large-scale 3D MRI data. To address these limitations, we propose the use of Vision Mamba, an advanced model based on State Space Models (SSMs), for the classification of 3D MRI images to detect Alzheimer's disease. Vision Mamba leverages dynamic state representations and the selective scan algorithm, allowing it to efficiently capture and retain important spatial information across 3D volumes. By dynamically adjusting state transitions based on input features, Vision Mamba can selectively retain relevant information, leading to more accurate and computationally efficient processing of 3D MRI data. Our approach combines the parallelizable nature of convolutional operations during training with the efficient, recurrent processing of states during inference. This architecture not only improves computational efficiency but also enhances the model's ability to handle long-range dependencies within 3D medical images. Experimental results demonstrate that Vision Mamba outperforms traditional CNN and Transformer models accuracy, making it a promising tool for the early detection of Alzheimer's disease using 3D MRI data.