# Markov Chain Monte Carlo with Gaussian Process Emulation for a 1D Hemodynamics Model of CTEPH

arXiv: https://arxiv.org/abs/2406.01599 · HTML: https://mlsanity.com/paper/2406.01599/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 0 of its 2 references that are in the map.
- First posted on arXiv 25 Apr 2024.

## Built on by (most cited first, 1 of 1)

- [Unveiling Processing--Property Relationships in Laser Powder Bed Fusion: The Synergy of Machine Learning and High-throughput Experiments](https://mlsanity.com/paper/2409.00248/) (2024)

## Abstract (arXiv)

Microvascular disease is a contributor to persistent pulmonary hypertension in those with chronic thromboembolic pulmonary hypertension (CTEPH). The heterogenous nature of the micro and macrovascular defects motivates the use of personalized computational models, which can predict flow dynamics within multiple generations of the arterial tree and into the microvasculature. Our study uses computational hemodynamics models and Gaussian processes for rapid, subject-specific calibration using retrospective data from a large animal model of CTEPH. Our subject-specific predictions shed light on microvascular dysfunction and arterial wall shear stress changes in CTEPH.
