# End-to-End Model-based Deep Learning for Dual-Energy Computed Tomography Material Decomposition

arXiv: https://arxiv.org/abs/2406.00479 · HTML: https://mlsanity.com/paper/2406.00479/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 4 of its 19 references that are in the map.
- First posted on arXiv 1 Jun 2024.

## Builds on (most cited first, 4 of 4)

- [Deep Convolutional Neural Network for Inverse Problems in Imaging](https://mlsanity.com/paper/1611.03679/) (2016)
- [MoDL: Model Based Deep Learning Architecture for Inverse Problems](https://mlsanity.com/paper/1712.02862/) (2017)
- [A material decomposition method for dual-energy CT via dual interactive Wasserstein generative adversarial networks](https://mlsanity.com/paper/2007.11247/) (2020)
- [Regularization by Denoising Sub-sampled Newton Method for Spectral CT Multi-Material Decomposition](https://mlsanity.com/paper/2103.13909/) (2021)

## Built on by (most cited first, 1 of 1)

- [SpectralCTGaussians: Projection-Domain Reconstruction and Basis Material Decomposition for Spectral CT using 3D Gaussian Splatting](https://mlsanity.com/paper/2609.29638/) (2026)

## Abstract (arXiv)

Dual energy X-ray Computed Tomography (DECT) enables to automatically decompose materials in clinical images without the manual segmentation using the dependency of the X-ray linear attenuation with energy. In this work we propose a deep learning procedure called End-to-End Material Decomposition (E2E-DEcomp) for quantitative material decomposition which directly convert the CT projection data into material images. The algorithm is based on incorporating the knowledge of the spectral model DECT system into the deep learning training loss and combining a data-learned prior in the material image domain. Furthermore, the training does not require any energy-based images in the dataset but rather only sinogram and material images. We show the effectiveness of the proposed direct E2E-DEcomp method on the AAPM spectral CT dataset (Sidky and Pan, 2023) compared with state of the art supervised deep learning networks.