# Quality Sentinel: Estimating Label Quality and Errors in Medical Segmentation Datasets

arXiv: https://arxiv.org/abs/2406.00327 · HTML: https://mlsanity.com/paper/2406.00327/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 52 references that are in the map.
- First posted on arXiv 1 Jun 2024.

## Builds on (most cited first, 30 of 30)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [Deep Bayesian Active Learning with Image Data](https://mlsanity.com/paper/1703.02910/) (2017)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysis](https://mlsanity.com/paper/2111.14791/) (2021)
- [Learning Loss for Active Learning](https://mlsanity.com/paper/1905.03677/) (2019)
- [AbdomenCT-1K: Is Abdominal Organ Segmentation A Solved Problem?](https://mlsanity.com/paper/2010.14808/) (2020)
- [CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection](https://mlsanity.com/paper/2301.00785/) (2023)
- [DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation](https://mlsanity.com/paper/1506.06448/) (2015)
- [A Survey on Active Learning and Human-in-the-Loop Deep Learning for Medical Image Analysis](https://mlsanity.com/paper/1910.02923/) (2019)
- [STU-Net: Scalable and Transferable Medical Image Segmentation Models Empowered by Large-Scale Supervised Pre-training](https://mlsanity.com/paper/2304.06716/) (2023)
- [Efficient Active Learning for Image Classification and Segmentation using a Sample Selection and Conditional Generative Adversarial Network](https://mlsanity.com/paper/1806.05473/) (2018)
- [Medical Image Understanding with Pretrained Vision Language Models: A Comprehensive Study](https://mlsanity.com/paper/2209.15517/) (2022)
- [AbdomenAtlas-8K: Annotating 8,000 CT Volumes for Multi-Organ Segmentation in Three Weeks](https://mlsanity.com/paper/2305.09666/) (2023)
- [Unleashing the Strengths of Unlabeled Data in Pan-cancer Abdominal Organ Quantification: the FLARE22 Challenge](https://mlsanity.com/paper/2308.05862/) (2023)
- [MultiTalent: A Multi-Dataset Approach to Medical Image Segmentation](https://mlsanity.com/paper/2303.14444/) (2023)
- [Leveraging Uncertainty Estimates for Predicting Segmentation Quality](https://mlsanity.com/paper/1807.00502/) (2018)
- [Real-time Prediction of Segmentation Quality](https://mlsanity.com/paper/1806.06244/) (2018)
- [Automatic CNN-based detection of cardiac MR motion artefacts using k-space data augmentation and curriculum learning](https://mlsanity.com/paper/1810.12185/) (2018)
- [Towards Unifying Anatomy Segmentation: Automated Generation of a Full-body CT Dataset via Knowledge Aggregation and Anatomical Guidelines](https://mlsanity.com/paper/2307.13375/) (2023)
- [Learning-Based Quality Control for Cardiac MR Images](https://mlsanity.com/paper/1803.09354/) (2018)

## Built on by (most cited first, 2 of 2)

- [Towards Ground-truth-free Evaluation of Any Segmentation in Medical Images](https://mlsanity.com/paper/2409.14874/) (2024)
- [HyperSORT: Self-Organising Robust Training with hyper-networks](https://mlsanity.com/paper/2506.21430/) (2025)

## Abstract (arXiv)

An increasing number of public datasets have shown a transformative impact on automated medical segmentation. However, these datasets are often with varying label quality, ranging from manual expert annotations to AI-generated pseudo-annotations. There is no systematic, reliable, and automatic quality control (QC). To fill in this bridge, we introduce a regression model, Quality Sentinel, to estimate label quality compared with manual annotations in medical segmentation datasets. This regression model was trained on over 4 million image-label pairs created by us. Each pair presents a varying but quantified label quality based on manual annotations, which enable us to predict the label quality of any image-label pairs in the inference. Our Quality Sentinel can predict the label quality of 142 body structures. The predicted label quality quantified by Dice Similarity Coefficient (DSC) shares a strong correlation with ground truth quality, with a positive correlation coefficient (r=0.902). Quality Sentinel has found multiple impactful use cases. (I) We evaluated label quality in publicly available datasets, where quality highly varies across different datasets. Our analysis also uncovers that male and younger subjects exhibit significantly higher quality. (II) We identified and corrected poorly annotated labels, achieving 1/3 reduction in annotation costs with optimal budgeting on TotalSegmentator. (III) We enhanced AI training efficiency and performance by focusing on high-quality pseudo labels, resulting in a 33%--88% performance boost over entropy-based methods, with a cost of 31% time and 4.5% memory. The data and model are released.
