# MindFormer: Semantic Alignment of Multi-Subject fMRI for Brain Decoding

arXiv: https://arxiv.org/abs/2405.17720 · HTML: https://mlsanity.com/paper/2405.17720/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 39 of its 60 references that are in the map.
- First posted on arXiv 28 May 2024.

## Builds on (most cited first, 30 of 39)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Unsupervised Learning of Visual Features by Contrasting Cluster Assignments](https://mlsanity.com/paper/2006.09882/) (2020)
- [Large Scale GAN Training for High Fidelity Natural Image Synthesis](https://mlsanity.com/paper/1809.11096/) (2018)
- [CIDEr: Consensus-based Image Description Evaluation](https://mlsanity.com/paper/1411.5726/) (2014)
- [IP-Adapter: Text Compatible Image Prompt Adapter for Text-to-Image Diffusion Models](https://mlsanity.com/paper/2308.06721/) (2023)
- [T2I-Adapter: Learning Adapters to Dig out More Controllable Ability for Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.08453/) (2023)
- [SPICE: Semantic Propositional Image Caption Evaluation](https://mlsanity.com/paper/1607.08822/) (2016)
- [Self-Attention Generative Adversarial Networks](https://mlsanity.com/paper/1805.08318/) (2018)
- [Versatile Diffusion: Text, Images and Variations All in One Diffusion Model](https://mlsanity.com/paper/2211.08332/) (2022)
- [Reconstructing the Mind's Eye: fMRI-to-Image with Contrastive Learning and Diffusion Priors](https://mlsanity.com/paper/2305.18274/) (2023)
- [Seeing Beyond the Brain: Conditional Diffusion Model with Sparse Masked Modeling for Vision Decoding](https://mlsanity.com/paper/2211.06956/) (2022)
- [Decoding speech perception from non-invasive brain recordings](https://mlsanity.com/paper/2208.12266/) (2022)
- [Generic decoding of seen and imagined objects using hierarchical visual features](https://mlsanity.com/paper/1510.06479/) (2015)
- [Natural scene reconstruction from fMRI signals using generative latent diffusion](https://mlsanity.com/paper/2303.05334/) (2023)
- [Mind Reader: Reconstructing complex images from brain activities](https://mlsanity.com/paper/2210.01769/) (2022)
- [From voxels to pixels and back: Self-supervision in natural-image reconstruction from fMRI](https://mlsanity.com/paper/1907.02431/) (2019)

## Built on by (most cited first, 4 of 4)

- [Toward Generalizing Visual Brain Decoding to Unseen Subjects](https://mlsanity.com/paper/2410.14445/) (2024)
- [Towards Interpretable Visual Decoding with Attention to Brain Representations](https://mlsanity.com/paper/2509.23566/) (2025)
- [Duala: Dual-Level Alignment of Subjects and Stimuli for Cross-Subject fMRI Decoding](https://mlsanity.com/paper/2603.07625/) (2026)
- [MindAlign: Decoding Inner Speech from fMRI Signals via Multimodal Embedding Alignment under Limited Data](https://mlsanity.com/paper/2606.20696/) (2026)

## Abstract (arXiv)

Research efforts for visual decoding from fMRI signals have attracted considerable attention in research community. Still multi-subject fMRI decoding with one model has been considered intractable due to the drastic variations in fMRI signals between subjects and even within the same subject across different trials. To address current limitations in multi-subject brain decoding, here we introduce a novel semantic alignment method of multi-subject fMRI signals using so-called MindFormer. This model is specifically designed to generate fMRI-conditioned feature vectors that can be used for conditioning Stable Diffusion model for fMRI- to-image generation or large language model (LLM) for fMRI-to-text generation. More specifically, MindFormer incorporates two key innovations: 1) a subject specific token that effectively capture individual differences in fMRI signals while synergistically combines multi subject fMRI data for training, and 2) a novel feature embedding and training scheme based on the IP-Adapter to extract semantically meaningful features from fMRI signals. Our experimental results demonstrate that MindFormer generates semantically consistent images and text across different subjects. Since our MindFormer maintains semantic fidelity by fully utilizing the training data across different subjects by significantly surpassing existing models in multi-subject brain decoding, this may help deepening our understanding of neural processing variations among individuals.