# A Novel Fusion Architecture for PD Detection Using Semi-Supervised Speech Embeddings

arXiv: https://arxiv.org/abs/2405.17206 · HTML: https://mlsanity.com/paper/2405.17206/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 16 of its 56 references that are in the map.
- First posted on arXiv 21 May 2024.

## Builds on (most cited first, 16 of 16)

- [Robust Speech Recognition via Large-Scale Weak Supervision](https://mlsanity.com/paper/2212.04356/) (2022)
- [wav2vec 2.0: A Framework for Self-Supervised Learning of Speech Representations](https://mlsanity.com/paper/2006.11477/) (2020)
- [HuBERT: Self-Supervised Speech Representation Learning by Masked Prediction of Hidden Units](https://mlsanity.com/paper/2106.07447/) (2021)
- [ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Tasks](https://mlsanity.com/paper/1908.02265/) (2019)
- [WavLM: Large-Scale Self-Supervised Pre-Training for Full Stack Speech Processing](https://mlsanity.com/paper/2110.13900/) (2021)
- [LXMERT: Learning Cross-Modality Encoder Representations from Transformers](https://mlsanity.com/paper/1908.07490/) (2019)
- [VisualBERT: A Simple and Performant Baseline for Vision and Language](https://mlsanity.com/paper/1908.03557/) (2019)
- [ViLT: Vision-and-Language Transformer Without Convolution or Region Supervision](https://mlsanity.com/paper/2102.03334/) (2021)
- [ImageBind: One Embedding Space To Bind Them All](https://mlsanity.com/paper/2305.05665/) (2023)
- [UniVL: A Unified Video and Language Pre-Training Model for Multimodal Understanding and Generation](https://mlsanity.com/paper/2002.06353/) (2020)
- [Transformer Dissection: A Unified Understanding of Transformer's Attention via the Lens of Kernel](https://mlsanity.com/paper/1908.11775/) (2019)
- [Multimodal Masked Autoencoders Learn Transferable Representations](https://mlsanity.com/paper/2205.14204/) (2022)
- [Using AI to Measure Parkinson's Disease Severity at Home](https://mlsanity.com/paper/2303.17573/) (2023)
- [Fine-Tuned Self-Supervised Speech Representations for Language Diarization in Multilingual Code-Switched Speech](https://mlsanity.com/paper/2312.09645/) (2023)
- [EchoWear: Smartwatch Technology for Voice and Speech Treatments of Patients with Parkinson's Disease](https://mlsanity.com/paper/1612.07608/) (2016)
- [Unmasking Parkinson's Disease with Smile: An AI-enabled Screening Framework](https://mlsanity.com/paper/2308.02588/) (2023)

## Built on by (most cited first, 1 of 1)

- [Accessible, At-Home Detection of Parkinson's Disease via Multi-task Video Analysis](https://mlsanity.com/paper/2406.14856/) (2024)

## Abstract (arXiv)

We present a framework to recognize Parkinson's disease (PD) through an English pangram utterance speech collected using a web application from diverse recording settings and environments, including participants' homes. Our dataset includes a global cohort of 1306 participants, including 392 diagnosed with PD. Leveraging the diversity of the dataset, spanning various demographic properties (such as age, sex, and ethnicity), we used deep learning embeddings derived from semi-supervised models such as Wav2Vec 2.0, WavLM, and ImageBind representing the speech dynamics associated with PD. Our novel fusion model for PD classification, which aligns different speech embeddings into a cohesive feature space, demonstrated superior performance over standard concatenation-based fusion models and other baselines (including models built on traditional acoustic features). In a randomized data split configuration, the model achieved an Area Under the Receiver Operating Characteristic Curve (AUROC) of 88.94% and an accuracy of 85.65%. Rigorous statistical analysis confirmed that our model performs equitably across various demographic subgroups in terms of sex, ethnicity, and age, and remains robust regardless of disease duration. Furthermore, our model, when tested on two entirely unseen test datasets collected from clinical settings and from a PD care center, maintained AUROC scores of 82.12% and 78.44%, respectively. This affirms the model's robustness and it's potential to enhance accessibility and health equity in real-world applications.