# Solving the enigma: Enhancing faithfulness and comprehensibility in explanations of deep networks

arXiv: https://arxiv.org/abs/2405.10008 · HTML: https://mlsanity.com/paper/2405.10008/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 22 of its 44 references that are in the map.
- First posted on arXiv 16 May 2024.

## Builds on (most cited first, 22 of 22)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [A Survey on Explainable Artificial Intelligence (XAI): Towards Medical XAI](https://mlsanity.com/paper/1907.07374/) (2019)
- [Explain Yourself! Leveraging Language Models for Commonsense Reasoning](https://mlsanity.com/paper/1906.02361/) (2019)
- [On the (In)fidelity and Sensitivity for Explanations](https://mlsanity.com/paper/1901.09392/) (2019)
- [Evaluating and Aggregating Feature-based Model Explanations](https://mlsanity.com/paper/2005.00631/) (2020)
- [Quantus: An Explainable AI Toolkit for Responsible Evaluation of Neural Network Explanations and Beyond](https://mlsanity.com/paper/2202.06861/) (2022)
- [FastSHAP: Real-Time Shapley Value Estimation](https://mlsanity.com/paper/2107.07436/) (2021)
- [Explainable Artificial Intelligence (XAI) 2.0: A Manifesto of Open Challenges and Interdisciplinary Research Directions](https://mlsanity.com/paper/2310.19775/) (2023)
- [Explainable deep learning models in medical image analysis](https://mlsanity.com/paper/2005.13799/) (2020)
- [Sampling Permutations for Shapley Value Estimation](https://mlsanity.com/paper/2104.12199/) (2021)
- [Approximating the Shapley Value without Marginal Contributions](https://mlsanity.com/paper/2302.00736/) (2023)
- [Investigating the fidelity of explainable artificial intelligence methods for applications of convolutional neural networks in geoscience](https://mlsanity.com/paper/2202.03407/) (2022)
- [Neural Network Attribution Methods for Problems in Geoscience: A Novel Synthetic Benchmark Dataset](https://mlsanity.com/paper/2103.10005/) (2021)
- [A novel framework employing deep multi-attention channels network for the autonomous detection of metastasizing cells through fluorescence microscopy](https://mlsanity.com/paper/2309.00911/) (2023)
- [An explainable three dimension framework to uncover learning patterns: A unified look in variable sulci recognition](https://mlsanity.com/paper/2309.00903/) (2023)

## Built on by (most cited first, 2 of 2)

- [Uncovering Neuroimaging Biomarkers of Brain Tumor Surgery with AI-Driven Methods](https://mlsanity.com/paper/2507.04881/) (2025)
- [A Framework for Evaluating Faithfulness in Explainable AI for Machine Anomalous Sound Detection Using Frequency-Band Perturbation](https://mlsanity.com/paper/2601.19017/) (2026)

## Abstract (arXiv)

The accelerated progress of artificial intelligence (AI) has popularized deep learning models across various domains, yet their inherent opacity poses challenges, particularly in critical fields like healthcare, medicine, and the geosciences. Explainable AI (XAI) has emerged to shed light on these 'black box' models, aiding in deciphering their decision-making processes. However, different XAI methods often produce significantly different explanations, leading to high inter-method variability that increases uncertainty and undermines trust in deep networks' predictions. In this study, we address this challenge by introducing a novel framework designed to enhance the explainability of deep networks through a dual focus on maximizing both accuracy and comprehensibility in the explanations. Our framework integrates outputs from multiple established XAI methods and leverages a non-linear neural network model, termed the 'explanation optimizer,' to construct a unified, optimal explanation. The optimizer evaluates explanations using two key metrics: faithfulness (accuracy in reflecting the network's decisions) and complexity (comprehensibility). By balancing these, it provides accurate and accessible explanations, addressing a key XAI limitation. Experiments on multi-class and binary classification in 2D object and 3D neuroscience imaging confirm its efficacy. Our optimizer achieved faithfulness scores 155% and 63% higher than the best XAI methods in 3D and 2D tasks, respectively, while also reducing complexity for better understanding. These results demonstrate that optimal explanations based on specific quality criteria are achievable, offering a solution to the issue of inter-method variability in the current XAI literature and supporting more trustworthy deep network predictions