# ECG-SMART-NET: A Deep Learning Architecture for Precise ECG Diagnosis of Occlusion Myocardial Infarction

arXiv: https://arxiv.org/abs/2405.09567 · HTML: https://mlsanity.com/paper/2405.09567/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 7 of its 43 references that are in the map.
- First posted on arXiv 8 May 2024.

## Builds on (most cited first, 7 of 7)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Deep Inside Convolutional Networks: Visualising Image Classification Models and Saliency Maps](https://mlsanity.com/paper/1312.6034/) (2013)
- [Natural Language Processing: State of The Art, Current Trends and Challenges](https://mlsanity.com/paper/1708.05148/) (2017)
- [Improving ECG Classification Interpretability using Saliency Maps](https://mlsanity.com/paper/2201.04070/) (2022)
- [Interpreting Deep Neural Networks for Single-Lead ECG Arrhythmia Classification](https://mlsanity.com/paper/2004.05399/) (2020)
- [ECG Heartbeat classification using deep transfer learning with Convolutional Neural Network and STFT technique](https://mlsanity.com/paper/2206.14200/) (2022)

## Built on by (most cited first, 1 of 1)

- [Fusion of ECG Foundation Model Embeddings to Improve Early Detection of Acute Coronary Syndromes](https://mlsanity.com/paper/2502.17476/) (2025)

## Abstract (arXiv)

Objective: In this paper we develop and evaluate ECG-SMART-NET for occlusion myocardial infarction (OMI) identification. OMI is a severe form of heart attack characterized by complete blockage of one or more coronary arteries requiring immediate referral for cardiac catheterization to restore blood flow to the heart. Two thirds of OMI cases are difficult to visually identify from a 12-lead electrocardiogram (ECG) and can be potentially fatal if not identified quickly. Previous works on this topic are scarce, and current state-of-the-art evidence suggests both feature-based random forests and convolutional neural networks (CNNs) are promising approaches to improve ECG detection of OMI. Methods: While the ResNet architecture has been adapted for use with ECG recordings, it is not ideally suited to capture informative temporal features within each lead and the spatial concordance or discordance across leads. We propose a clinically informed modification of the ResNet-18 architecture. The model first learns temporal features through temporal convolutional layers with 1xk kernels followed by a spatial convolutional layer, after the residual blocks, with 12x1 kernels to learn spatial features. Results: ECG-SMART-NET was benchmarked against the original ResNet-18 and other state-of-the-art models on a multisite real-word clinical dataset that consists of 10,393 ECGs from 7,397 unique patients (rate of OMI =7.2%). ECG-SMART-NET outperformed other models in the classification of OMI with a test AUC of 0.953 [0.921, 0.978]. Conclusion and Significance: ECG-SMART-NET can outperform the state-of-the-art random forest for OMI prediction and is better suited for this task than the original ResNet-18 architecture.
