# Meta-Learned Modality-Weighted Knowledge Distillation for Robust Multi-Modal Learning with Missing Data

arXiv: https://arxiv.org/abs/2405.07155 · HTML: https://mlsanity.com/paper/2405.07155/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Placed in Distillation for medical imaging, one of 12 directions in Knowledge distillation.
- Builds on 36 of its 59 references that are in the map.
- First posted on arXiv 12 May 2024.

## Placed in

- Knowledge distillation / [Distillation for medical imaging](https://mlsanity.com/distill/distillation-for-medical-imaging/)

## Builds on (most cited first, 30 of 36)

- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [SGDR: Stochastic Gradient Descent with Warm Restarts](https://mlsanity.com/paper/1608.03983/) (2016)
- [Conditional Generative Adversarial Nets](https://mlsanity.com/paper/1411.1784/) (2014)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [Multi-Modal Fusion Transformer for End-to-End Autonomous Driving](https://mlsanity.com/paper/2104.09224/) (2021)
- [Diverse Image-to-Image Translation via Disentangled Representations](https://mlsanity.com/paper/1808.00948/) (2018)
- [SMIL: Multimodal Learning with Severely Missing Modality](https://mlsanity.com/paper/2103.05677/) (2021)
- [Multimodal Contrastive Learning with LIMoE: the Language-Image Mixture of Experts](https://mlsanity.com/paper/2206.02770/) (2022)
- [Are Multimodal Transformers Robust to Missing Modality?](https://mlsanity.com/paper/2204.05454/) (2022)
- [Localizing Visual Sounds the Hard Way](https://mlsanity.com/paper/2104.02691/) (2021)
- [Multi-modal Learning with Missing Modality via Shared-Specific Feature Modelling](https://mlsanity.com/paper/2307.14126/) (2023)
- [Multimodal Prompting with Missing Modalities for Visual Recognition](https://mlsanity.com/paper/2303.03369/) (2023)
- [Deep Multimodal Fusion by Channel Exchanging](https://mlsanity.com/paper/2011.05005/) (2020)
- [HeMIS: Hetero-Modal Image Segmentation](https://mlsanity.com/paper/1607.05194/) (2016)
- [Stochastic Segmentation Networks: Modelling Spatially Correlated Aleatoric Uncertainty](https://mlsanity.com/paper/2006.06015/) (2020)
- [mmFormer: Multimodal Medical Transformer for Incomplete Multimodal Learning of Brain Tumor Segmentation](https://mlsanity.com/paper/2206.02425/) (2022)
- [Trusted Multi-View Classification](https://mlsanity.com/paper/2102.02051/) (2021)
- [VL-Mamba: Exploring State Space Models for Multimodal Learning](https://mlsanity.com/paper/2403.13600/) (2024)
- [CentralNet: a Multilayer Approach for Multimodal Fusion](https://mlsanity.com/paper/1808.07275/) (2018)
- [Unpaired Multi-modal Segmentation via Knowledge Distillation](https://mlsanity.com/paper/2001.03111/) (2020)
- [Hetero-Modal Variational Encoder-Decoder for Joint Modality Completion and Segmentation](https://mlsanity.com/paper/1907.11150/) (2019)
- [Robust Multimodal Brain Tumor Segmentation via Feature Disentanglement and Gated Fusion](https://mlsanity.com/paper/2002.09708/) (2020)
- [Knowledge distillation from multi-modal to mono-modal segmentation networks](https://mlsanity.com/paper/2106.09564/) (2021)
- [Emotion Recognition in Speech using Cross-Modal Transfer in the Wild](https://mlsanity.com/paper/1808.05561/) (2018)
- [ACN: Adversarial Co-training Network for Brain Tumor Segmentation with Missing Modalities](https://mlsanity.com/paper/2106.14591/) (2021)
- [Brain Tumor Segmentation on MRI with Missing Modalities](https://mlsanity.com/paper/1904.07290/) (2019)
- [Latent Correlation Representation Learning for Brain Tumor Segmentation with Missing MRI Modalities](https://mlsanity.com/paper/2104.06231/) (2021)
- [Soft Expert Reward Learning for Vision-and-Language Navigation](https://mlsanity.com/paper/2007.10835/) (2020)
- [Space-Time Crop & Attend: Improving Cross-modal Video Representation Learning](https://mlsanity.com/paper/2103.10211/) (2021)
- [SMU-Net: Style matching U-Net for brain tumor segmentation with missing modalities](https://mlsanity.com/paper/2204.02961/) (2022)

## Built on by (most cited first, 5 of 5)

- [Global-Local Distillation Network-Based Audio-Visual Speaker Tracking with Incomplete Modalities](https://mlsanity.com/paper/2408.14585/) (2024)
- [PGAD: Prototype-Guided Adaptive Distillation for Multi-Modal Learning in AD Diagnosis](https://mlsanity.com/paper/2503.04836/) (2025)
- [Purify-then-Align: Towards Robust Human Sensing under Modality Missing with Knowledge Distillation from Noisy Multimodal Teacher](https://mlsanity.com/paper/2604.05584/) (2026)
- [Unifying Depth and Width Pruning for LLMs via Binary Knapsack Optimization](https://mlsanity.com/paper/2608.12953/) (2026)
- [LASSNet: Level-Aware Availability-Conditioned Spatial-Semantic Fusion for Brain Tumor Segmentation with Missing MRI Modalities](https://mlsanity.com/paper/2609.06733/) (2026)

## Abstract (arXiv)

In multi-modal learning, some modalities are more influential than others, and their absence can have a significant impact on classification/segmentation accuracy. Addressing this challenge, we propose a novel approach called Meta-learned Modality-weighted Knowledge Distillation (MetaKD), which enables multi-modal models to maintain high accuracy even when key modalities are missing. MetaKD adaptively estimates the importance weight of each modality through a meta-learning process. These learned importance weights guide a pairwise modality-weighted knowledge distillation process, allowing high-importance modalities to transfer knowledge to lower-importance ones, resulting in robust performance despite missing inputs. Unlike previous methods in the field, which are often task-specific and require significant modifications, our approach is designed to work in multiple tasks (e.g., segmentation and classification) with minimal adaptation. Experimental results on five prevalent datasets, including three Brain Tumor Segmentation datasets (BraTS2018, BraTS2019 and BraTS2020), the Alzheimer's Disease Neuroimaging Initiative (ADNI) classification dataset and the Audiovision-MNIST classification dataset, demonstrate the proposed model is able to outperform the compared models by a large margin. The code is available at https://github.com/billhhh/MetaKD.
