# AC-MAMBASEG: An adaptive convolution and Mamba-based architecture for enhanced skin lesion segmentation

arXiv: https://arxiv.org/abs/2405.03011 · HTML: https://mlsanity.com/paper/2405.03011/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba).
- Builds on 28 of its 45 references that are in the map.
- First posted on arXiv 5 May 2024.

## Placed in

- State-space sequence models (S4, Mamba) / [Mamba for medical image analysis](https://mlsanity.com/ssm/mamba-for-medical-image-analysis/)

## Builds on (most cited first, 28 of 28)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Efficiently Modeling Long Sequences with Structured State Spaces](https://mlsanity.com/paper/2111.00396/) (2021)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation](https://mlsanity.com/paper/1511.00561/) (2015)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Instance Normalization: The Missing Ingredient for Fast Stylization](https://mlsanity.com/paper/1607.08022/) (2016)
- [Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Model](https://mlsanity.com/paper/2401.09417/) (2024)
- [VMamba: Visual State Space Model](https://mlsanity.com/paper/2401.10166/) (2024)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [U-Mamba: Enhancing Long-range Dependency for Biomedical Image Segmentation](https://mlsanity.com/paper/2401.04722/) (2024)
- [Selective Kernel Networks](https://mlsanity.com/paper/1903.06586/) (2019)
- [VM-UNet: Vision Mamba UNet for Medical Image Segmentation](https://mlsanity.com/paper/2402.02491/) (2024)
- [Tversky loss function for image segmentation using 3D fully convolutional deep networks](https://mlsanity.com/paper/1706.05721/) (2017)
- [State Space Models for Event Cameras](https://mlsanity.com/paper/2402.15584/) (2024)
- [LightM-UNet: Mamba Assists in Lightweight UNet for Medical Image Segmentation](https://mlsanity.com/paper/2403.05246/) (2024)
- [UltraLight VM-UNet: Parallel Vision Mamba Significantly Reduces Parameters for Skin Lesion Segmentation](https://mlsanity.com/paper/2403.20035/) (2024)
- [MambaMixer: Efficient Selective State Space Models with Dual Token and Channel Selection](https://mlsanity.com/paper/2403.19888/) (2024)
- [Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentation](https://mlsanity.com/paper/2402.10887/) (2024)
- [DSNet: Automatic Dermoscopic Skin Lesion Segmentation](https://mlsanity.com/paper/1907.04305/) (2019)
- [Res-VMamba: Fine-Grained Food Category Visual Classification Using Selective State Space Models with Deep Residual Learning](https://mlsanity.com/paper/2402.15761/) (2024)
- [HSIMamba: Hyperpsectral Imaging Efficient Feature Learning with Bidirectional State Space for Classification](https://mlsanity.com/paper/2404.00272/) (2024)
- [MambaPupil: Bidirectional Selective Recurrent model for Event-based Eye tracking](https://mlsanity.com/paper/2404.12083/) (2024)
- [Cross-CBAM: A Lightweight network for Scene Segmentation](https://mlsanity.com/paper/2306.02306/) (2023)

## Built on by (most cited first, 6 of 6)

- [Mamba in Vision: A Comprehensive Survey of Techniques and Applications](https://mlsanity.com/paper/2410.03105/) (2024)
- [OCTAMamba: A State-Space Model Approach for Precision OCTA Vasculature Segmentation](https://mlsanity.com/paper/2409.08000/) (2024)
- [MambaU-Lite: A Lightweight Model based on Mamba and Integrated Channel-Spatial Attention for Skin Lesion Segmentation](https://mlsanity.com/paper/2412.01405/) (2024)
- [Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentation](https://mlsanity.com/paper/2503.19589/) (2025)
- [APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms](https://mlsanity.com/paper/2606.30577/) (2026)
- [An Ultra-Widefield Swept-Source OCTA Dataset and a Polar-Gated Mamba Network for Retinal Vessel Segmentation](https://mlsanity.com/paper/2609.12574/) (2026)

## Abstract (arXiv)

Skin lesion segmentation is a critical task in computer-aided diagnosis systems for dermatological diseases. Accurate segmentation of skin lesions from medical images is essential for early detection, diagnosis, and treatment planning. In this paper, we propose a new model for skin lesion segmentation namely AC-MambaSeg, an enhanced model that has the hybrid CNN-Mamba backbone, and integrates advanced components such as Convolutional Block Attention Module (CBAM), Attention Gate, and Selective Kernel Bottleneck. AC-MambaSeg leverages the Vision Mamba framework for efficient feature extraction, while CBAM and Selective Kernel Bottleneck enhance its ability to focus on informative regions and suppress background noise. We evaluate the performance of AC-MambaSeg on diverse datasets of skin lesion images including ISIC-2018 and PH2; then compare it against existing segmentation methods. Our model shows promising potential for improving computer-aided diagnosis systems and facilitating early detection and treatment of dermatological diseases. Our source code will be made available at: https://github.com/vietthanh2710/AC-MambaSeg.
