# Score-based Generative Priors Guided Model-driven Network for MRI Reconstruction

arXiv: https://arxiv.org/abs/2405.02958 · HTML: https://mlsanity.com/paper/2405.02958/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 52 of its 132 references that are in the map.
- First posted on arXiv 5 May 2024.

## Builds on (most cited first, 30 of 52)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Improved Techniques for Training Score-Based Generative Models](https://mlsanity.com/paper/2006.09011/) (2020)
- [fastMRI: An Open Dataset and Benchmarks for Accelerated MRI](https://mlsanity.com/paper/1811.08839/) (2018)
- [RefineNet: Multi-Path Refinement Networks for High-Resolution Semantic Segmentation](https://mlsanity.com/paper/1611.06612/) (2016)
- [Deep Convolutional Neural Network for Inverse Problems in Imaging](https://mlsanity.com/paper/1611.03679/) (2016)
- [MoDL: Model Based Deep Learning Architecture for Inverse Problems](https://mlsanity.com/paper/1712.02862/) (2017)
- [Learning a Variational Network for Reconstruction of Accelerated MRI Data](https://mlsanity.com/paper/1704.00447/) (2017)
- [Compressed Sensing using Generative Models](https://mlsanity.com/paper/1703.03208/) (2017)
- [Score-based diffusion models for accelerated MRI](https://mlsanity.com/paper/2110.05243/) (2021)
- [Robust Compressed Sensing MRI with Deep Generative Priors](https://mlsanity.com/paper/2108.01368/) (2021)
- [Cold Diffusion: Inverting Arbitrary Image Transforms Without Noise](https://mlsanity.com/paper/2208.09392/) (2022)
- [Diffusion Models for Medical Image Analysis: A Comprehensive Survey](https://mlsanity.com/paper/2211.07804/) (2022)
- [A Kernelized Stein Discrepancy for Goodness-of-fit Tests and Model Evaluation](https://mlsanity.com/paper/1602.03253/) (2016)
- [A Deep Cascade of Convolutional Neural Networks for Dynamic MR Image Reconstruction](https://mlsanity.com/paper/1704.02422/) (2017)
- [A Review on Generative Adversarial Networks: Algorithms, Theory, and Applications](https://mlsanity.com/paper/2001.06937/) (2020)
- [A Survey on Self-supervised Learning: Algorithms, Applications, and Future Trends](https://mlsanity.com/paper/2301.05712/) (2023)
- [End-to-End Variational Networks for Accelerated MRI Reconstruction](https://mlsanity.com/paper/2004.06688/) (2020)
- [Adaptive Diffusion Priors for Accelerated MRI Reconstruction](https://mlsanity.com/paper/2207.05876/) (2022)
- [Compressed Sensing MRI Reconstruction using a Generative Adversarial Network with a Cyclic Loss](https://mlsanity.com/paper/1709.00753/) (2017)
- [Towards performant and reliable undersampled MR reconstruction via diffusion model sampling](https://mlsanity.com/paper/2203.04292/) (2022)
- [Deep Residual Learning for Accelerated MRI using Magnitude and Phase Networks](https://mlsanity.com/paper/1804.00432/) (2018)
- [ReconFormer: Accelerated MRI Reconstruction Using Recurrent Transformer](https://mlsanity.com/paper/2201.09376/) (2022)
- [Neural Empirical Bayes](https://mlsanity.com/paper/1903.02334/) (2019)
- [High-Frequency Space Diffusion Models for Accelerated MRI](https://mlsanity.com/paper/2208.05481/) (2022)
- [Memory-Augmented Deep Unfolding Network for Compressive Sensing](https://mlsanity.com/paper/2110.09766/) (2021)
- [Self-Supervised MRI Reconstruction with Unrolled Diffusion Models](https://mlsanity.com/paper/2306.16654/) (2023)
- [Recurrent Variational Network: A Deep Learning Inverse Problem Solver applied to the task of Accelerated MRI Reconstruction](https://mlsanity.com/paper/2111.09639/) (2021)
- [VS-Net: Variable splitting network for accelerated parallel MRI reconstruction](https://mlsanity.com/paper/1907.10033/) (2019)

## Built on by (most cited first, 3 of 3)

- [Bifidelity Parameter Estimation Using Conditional Diffusion Models](https://mlsanity.com/paper/2504.01894/) (2025)
- [Sub-DM:Subspace Diffusion Model with Orthogonal Decomposition for MRI Reconstruction](https://mlsanity.com/paper/2411.03758/) (2024)
- [MRI Cross-Modal Synthesis: A Comparative Study of Generative Models for T1-to-T2 Reconstruction](https://mlsanity.com/paper/2602.07068/) (2026)

## Abstract (arXiv)

Score matching with Langevin dynamics (SMLD) method has been successfully applied to accelerated MRI. However, the hyperparameters in the sampling process require subtle tuning, otherwise the results can be severely corrupted by hallucination artifacts, especially with out-of-distribution test data. To address the limitations, we proposed a novel workflow where naive SMLD samples serve as additional priors to guide model-driven network training. First, we adopted a pretrained score network to generate samples as preliminary guidance images (PGI), obviating the need for network retraining, parameter tuning and in-distribution test data. Although PGIs are corrupted by hallucination artifacts, we believe they can provide extra information through effective denoising steps to facilitate reconstruction. Therefore, we designed a denoising module (DM) in the second step to coarsely eliminate artifacts and noises from PGIs. The features are extracted from a score-based information extractor (SIE) and a cross-domain information extractor (CIE), which directly map to the noise patterns. Third, we designed a model-driven network guided by denoised PGIs (DGIs) to further recover fine details. DGIs are densely connected with intermediate reconstructions in each cascade to enrich the information and are periodically updated to provide more accurate guidance. Our experiments on different datasets reveal that despite the low average quality of PGIs, the proposed workflow can effectively extract valuable information to guide the network training, even with severely reduced training data and sampling steps. Our method outperforms other cutting-edge techniques by effectively mitigating hallucination artifacts, yielding robust and high-quality reconstruction results.
