# MERIT: Multi-view evidential learning for reliable and interpretable liver fibrosis staging

arXiv: https://arxiv.org/abs/2405.02918 · HTML: https://mlsanity.com/paper/2405.02918/

## Key facts

- Cited by 12 papers in the map (data through 14 Oct 2026).
- Builds on 28 of its 66 references that are in the map.
- First posted on arXiv 5 May 2024.

## Builds on (most cited first, 28 of 28)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Dropout as a Bayesian Approximation: Representing Model Uncertainty in Deep Learning](https://mlsanity.com/paper/1506.02142/) (2015)
- [What Uncertainties Do We Need in Bayesian Deep Learning for Computer Vision?](https://mlsanity.com/paper/1703.04977/) (2017)
- [Improved Regularization of Convolutional Neural Networks with Cutout](https://mlsanity.com/paper/1708.04552/) (2017)
- [Contrastive Multiview Coding](https://mlsanity.com/paper/1906.05849/) (2019)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Multi-Scale Context Aggregation by Dilated Convolutions](https://mlsanity.com/paper/1511.07122/) (2015)
- [Two-Stream Convolutional Networks for Action Recognition in Videos](https://mlsanity.com/paper/1406.2199/) (2014)
- [A Review of Uncertainty Quantification in Deep Learning: Techniques, Applications and Challenges](https://mlsanity.com/paper/2011.06225/) (2020)
- [Evidential Deep Learning to Quantify Classification Uncertainty](https://mlsanity.com/paper/1806.01768/) (2018)
- [Predictive Uncertainty Estimation via Prior Networks](https://mlsanity.com/paper/1802.10501/) (2018)
- [Convolutional Two-Stream Network Fusion for Video Action Recognition](https://mlsanity.com/paper/1604.06573/) (2016)
- [Interpretable machine learning: definitions, methods, and applications](https://mlsanity.com/paper/1901.04592/) (2019)
- [Trusted Multi-View Classification with Dynamic Evidential Fusion](https://mlsanity.com/paper/2204.11423/) (2022)
- [On Deep Multi-View Representation Learning: Objectives and Optimization](https://mlsanity.com/paper/1602.01024/) (2016)
- [Masksembles for Uncertainty Estimation](https://mlsanity.com/paper/2012.08334/) (2020)
- [Understanding Softmax Confidence and Uncertainty](https://mlsanity.com/paper/2106.04972/) (2021)
- [Towards Learning Convolutions from Scratch](https://mlsanity.com/paper/2007.13657/) (2020)
- [Think Twice Before Selection: Federated Evidential Active Learning for Medical Image Analysis with Domain Shifts](https://mlsanity.com/paper/2312.02567/) (2023)
- [Robust Feature-Level Adversaries are Interpretability Tools](https://mlsanity.com/paper/2110.03605/) (2021)
- [Quantifying and Leveraging Predictive Uncertainty for Medical Image Assessment](https://mlsanity.com/paper/2007.04258/) (2020)
- [Layer Ensembles: A Single-Pass Uncertainty Estimation in Deep Learning for Segmentation](https://mlsanity.com/paper/2203.08878/) (2022)
- [Benchmarking common uncertainty estimation methods with histopathological images under domain shift and label noise](https://mlsanity.com/paper/2301.01054/) (2023)
- [A Reliable and Interpretable Framework of Multi-view Learning for Liver Fibrosis Staging](https://mlsanity.com/paper/2306.12054/) (2023)
- [Addressing Deep Learning Model Calibration Using Evidential Neural Networks and Uncertainty-Aware Training](https://mlsanity.com/paper/2301.13296/) (2023)

## Built on by (most cited first, 12 of 12)

- [KA2ER: Knowledge Adaptive Amalgamation of ExpeRts for Medical Images Segmentation](https://mlsanity.com/paper/2410.21085/) (2024)
- [Semi-supervised Liver Segmentation and Patch-based Fibrosis Staging with Registration-aided Multi-parametric MRI](https://mlsanity.com/paper/2602.09686/) (2026)
- [Search-MIND: Training-Free Multi-Modal Medical Image Registration](https://mlsanity.com/paper/2604.09743/) (2026)
- [How Far Has AI Come in Liver Fibrosis Staging? A Large-Scale Real-World Dataset and Benchmark](https://mlsanity.com/paper/2605.25595/) (2026)
- [Improved mmFormer for Liver Fibrosis Staging via Missing-Modality Compensation](https://mlsanity.com/paper/2509.16436/) (2025)
- [Multi-modal Liver Segmentation and Fibrosis Staging Using Real-world MRI Images](https://mlsanity.com/paper/2509.26061/) (2025)
- [The 1st Solution for CARE Liver Task Challenge 2025: Contrast-Aware Semi-Supervised Segmentation with Domain Generalization and Test-Time Adaptation](https://mlsanity.com/paper/2510.04243/) (2025)
- [Label-Efficient Cross-Modality Generalization for Liver Segmentation in Multi-Phase MRI](https://mlsanity.com/paper/2510.04705/) (2025)
- [SSL-MedSAM2: A Semi-supervised Medical Image Segmentation Framework Powered by Few-shot Learning of SAM2](https://mlsanity.com/paper/2512.11548/) (2025)
- [X-Edit: Exact, Explicit, and Explainable Null-Space Editing for Medical Vision Transformers](https://mlsanity.com/paper/2605.24932/) (2026)
- [CMCNet: Aligning Ultrasound Image Embeddings with Textual TI-RADS Representations for Fine-Grained Thyroid Classification](https://mlsanity.com/paper/2608.13939/) (2026)
- [DINO-Med: A Unified Patch-Based Adaptation Framework for Multi-Modal Medical Image Analysis Applied to Liver Fibrosis Staging](https://mlsanity.com/paper/2609.11380/) (2026)

## Abstract (arXiv)

Accurate staging of liver fibrosis from magnetic resonance imaging (MRI) is crucial in clinical practice. While conventional methods often focus on a specific sub-region, multi-view learning captures more information by analyzing multiple patches simultaneously. However, previous multi-view approaches could not typically calculate uncertainty by nature, and they generally integrate features from different views in a black-box fashion, hence compromising reliability as well as interpretability of the resulting models. In this work, we propose a new multi-view method based on evidential learning, referred to as MERIT, which tackles the two challenges in a unified framework. MERIT enables uncertainty quantification of the predictions to enhance reliability, and employs a logic-based combination rule to improve interpretability. Specifically, MERIT models the prediction from each sub-view as an opinion with quantified uncertainty under the guidance of the subjective logic theory. Furthermore, a distribution-aware base rate is introduced to enhance performance, particularly in scenarios involving class distribution shifts. Finally, MERIT adopts a feature-specific combination rule to explicitly fuse multi-view predictions, thereby enhancing interpretability. Results have showcased the effectiveness of the proposed MERIT, highlighting the reliability and offering both ad-hoc and post-hoc interpretability. They also illustrate that MERIT can elucidate the significance of each view in the decision-making process for liver fibrosis staging. Our code has be released via https://github.com/HenryLau7/MERIT.
