# Privacy-Preserving Statistical Data Generation: Application to Sepsis Detection

arXiv: https://arxiv.org/abs/2404.16638 · HTML: https://mlsanity.com/paper/2404.16638/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 7 of its 53 references that are in the map.
- First posted on arXiv 25 Apr 2024.

## Builds on (most cited first, 7 of 7)

- [Optuna: A Next-generation Hyperparameter Optimization Framework](https://mlsanity.com/paper/1907.10902/) (2019)
- [TabDDPM: Modelling Tabular Data with Diffusion Models](https://mlsanity.com/paper/2209.15421/) (2022)
- [Generating Multi-label Discrete Patient Records using Generative Adversarial Networks](https://mlsanity.com/paper/1703.06490/) (2017)
- [CTAB-GAN: Effective Table Data Synthesizing](https://mlsanity.com/paper/2102.08369/) (2021)
- [Boosting Deep Learning Risk Prediction with Generative Adversarial Networks for Electronic Health Records](https://mlsanity.com/paper/1709.01648/) (2017)
- [Generation of Synthetic Electronic Medical Record Text](https://mlsanity.com/paper/1812.02793/) (2018)
- [Ensembling Neural Networks for Improved Prediction and Privacy in Early Diagnosis of Sepsis](https://mlsanity.com/paper/2209.00439/) (2022)

## Abstract (arXiv)

The biomedical field is among the sectors most impacted by the increasing regulation of Artificial Intelligence (AI) and data protection legislation, given the sensitivity of patient information. However, the rise of synthetic data generation methods offers a promising opportunity for data-driven technologies. In this study, we propose a statistical approach for synthetic data generation applicable in classification problems. We assess the utility and privacy implications of synthetic data generated by Kernel Density Estimator and K-Nearest Neighbors sampling (KDE-KNN) within a real-world context, specifically focusing on its application in sepsis detection. The detection of sepsis is a critical challenge in clinical practice due to its rapid progression and potentially life-threatening consequences. Moreover, we emphasize the benefits of KDE-KNN compared to current synthetic data generation methodologies. Additionally, our study examines the effects of incorporating synthetic data into model training procedures. This investigation provides valuable insights into the effectiveness of synthetic data generation techniques in mitigating regulatory constraints within the biomedical field.