# Mitigating False Predictions In Unreasonable Body Regions

arXiv: https://arxiv.org/abs/2404.15718 · HTML: https://mlsanity.com/paper/2404.15718/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 26 references that are in the map.
- First posted on arXiv 24 Apr 2024.

## Builds on (most cited first, 13 of 13)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [The KiTS19 Challenge Data: 300 Kidney Tumor Cases with Clinical Context, CT Semantic Segmentations, and Surgical Outcomes](https://mlsanity.com/paper/1904.00445/) (2019)
- [MedNeXt: Transformer-driven Scaling of ConvNets for Medical Image Segmentation](https://mlsanity.com/paper/2303.09975/) (2023)
- [DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation](https://mlsanity.com/paper/1506.06448/) (2015)
- [STU-Net: Scalable and Transferable Medical Image Segmentation Models Empowered by Large-Scale Supervised Pre-training](https://mlsanity.com/paper/2304.06716/) (2023)
- [Methods and open-source toolkit for analyzing and visualizing challenge results](https://mlsanity.com/paper/1910.05121/) (2019)
- [Unleashing the Strengths of Unlabeled Data in Pan-cancer Abdominal Organ Quantification: the FLARE22 Challenge](https://mlsanity.com/paper/2308.05862/) (2023)
- [MultiTalent: A Multi-Dataset Approach to Medical Image Segmentation](https://mlsanity.com/paper/2303.14444/) (2023)
- [Cubic LSTMs for Video Prediction](https://mlsanity.com/paper/1904.09412/) (2019)
- [Extending nnU-Net is all you need](https://mlsanity.com/paper/2208.10791/) (2022)
- [Towards Robust General Medical Image Segmentation](https://mlsanity.com/paper/2107.04263/) (2021)

## Built on by (most cited first, 1 of 1)

- [LocBAM: Advancing 3D Patch-Based Image Segmentation by Integrating Location Contex](https://mlsanity.com/paper/2601.14802/) (2026)

## Abstract (arXiv)

Despite considerable strides in developing deep learning models for 3D medical image segmentation, the challenge of effectively generalizing across diverse image distributions persists. While domain generalization is acknowledged as vital for robust application in clinical settings, the challenges stemming from training with a limited Field of View (FOV) remain unaddressed. This limitation leads to false predictions when applied to body regions beyond the FOV of the training data. In response to this problem, we propose a novel loss function that penalizes predictions in implausible body regions, applicable in both single-dataset and multi-dataset training schemes. It is realized with a Body Part Regression model that generates axial slice positional scores. Through comprehensive evaluation using a test set featuring varying FOVs, our approach demonstrates remarkable improvements in generalization capabilities. It effectively mitigates false positive tumor predictions up to 85% and significantly enhances overall segmentation performance.
