# Multi-view X-ray Image Synthesis with Multiple Domain Disentanglement from CT Scans

arXiv: https://arxiv.org/abs/2404.11889 · HTML: https://mlsanity.com/paper/2404.11889/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 29 of its 64 references that are in the map.
- First posted on arXiv 18 Apr 2024.

## Builds on (most cited first, 29 of 29)

- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [3D Gaussian Splatting for Real-Time Radiance Field Rendering](https://mlsanity.com/paper/2308.04079/) (2023)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Image-to-Image Translation with Conditional Adversarial Networks](https://mlsanity.com/paper/1611.07004/) (2016)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [Progressive Growing of GANs for Improved Quality, Stability, and Variation](https://mlsanity.com/paper/1710.10196/) (2017)
- [Arbitrary Style Transfer in Real-time with Adaptive Instance Normalization](https://mlsanity.com/paper/1703.06868/) (2017)
- [Demystifying MMD GANs](https://mlsanity.com/paper/1801.01401/) (2018)
- [Challenging Common Assumptions in the Unsupervised Learning of Disentangled Representations](https://mlsanity.com/paper/1811.12359/) (2018)
- [pi-GAN: Periodic Implicit Generative Adversarial Networks for 3D-Aware Image Synthesis](https://mlsanity.com/paper/2012.00926/) (2020)
- [Interpreting the Latent Space of GANs for Semantic Face Editing](https://mlsanity.com/paper/1907.10786/) (2019)
- [Which Training Methods for GANs do actually Converge?](https://mlsanity.com/paper/1801.04406/) (2018)
- [Pivotal Tuning for Latent-based Editing of Real Images](https://mlsanity.com/paper/2106.05744/) (2021)
- [ReStyle: A Residual-Based StyleGAN Encoder via Iterative Refinement](https://mlsanity.com/paper/2104.02699/) (2021)
- [Editing in Style: Uncovering the Local Semantics of GANs](https://mlsanity.com/paper/2004.14367/) (2020)
- [SDF-StyleGAN: Implicit SDF-Based StyleGAN for 3D Shape Generation](https://mlsanity.com/paper/2206.12055/) (2022)
- [X2CT-GAN: Reconstructing CT from Biplanar X-Rays with Generative Adversarial Networks](https://mlsanity.com/paper/1905.06902/) (2019)
- [Advances in 3D Generation: A Survey](https://mlsanity.com/paper/2401.17807/) (2024)
- [DeepDRR -- A Catalyst for Machine Learning in Fluoroscopy-guided Procedures](https://mlsanity.com/paper/1803.08606/) (2018)
- [CTSpine1K: A Large-Scale Dataset for Spinal Vertebrae Segmentation in Computed Tomography](https://mlsanity.com/paper/2105.14711/) (2021)
- [MeshGAN: Non-linear 3D Morphable Models of Faces](https://mlsanity.com/paper/1903.10384/) (2019)
- [Fast Auto-Differentiable Digitally Reconstructed Radiographs for Solving Inverse Problems in Intraoperative Imaging](https://mlsanity.com/paper/2208.12737/) (2022)
- [End-To-End Convolutional Neural Network for 3D Reconstruction of Knee Bones From Bi-Planar X-Ray Images](https://mlsanity.com/paper/2004.00871/) (2020)
- [Domain Intersection and Domain Difference](https://mlsanity.com/paper/1908.11628/) (2019)
- [A survey on GANs for computer vision: Recent research, analysis and taxonomy](https://mlsanity.com/paper/2203.11242/) (2022)
- [i3PosNet: Instrument Pose Estimation from X-Ray in temporal bone surgery](https://mlsanity.com/paper/1802.09575/) (2018)
- [SD-GAN: Semantic Decomposition for Face Image Synthesis with Discrete Attribute](https://mlsanity.com/paper/2207.05300/) (2022)
- [MaTe3D: Mask-guided Text-based 3D-aware Portrait Editing](https://mlsanity.com/paper/2312.06947/) (2023)
- [TreeGAN: Incorporating Class Hierarchy into Image Generation](https://mlsanity.com/paper/2009.07734/) (2020)

## Built on by (most cited first, 1 of 1)

- [Robust and Accurate Multi-view 2D/3D Image Registration with Differentiable X-ray Rendering and Dual Cross-view Constraints](https://mlsanity.com/paper/2506.22191/) (2025)

## Abstract (arXiv)

X-ray images play a vital role in the intraoperative processes due to their high resolution and fast imaging speed and greatly promote the subsequent segmentation, registration and reconstruction. However, over-dosed X-rays superimpose potential risks to human health to some extent. Data-driven algorithms from volume scans to X-ray images are restricted by the scarcity of paired X-ray and volume data. Existing methods are mainly realized by modelling the whole X-ray imaging procedure. In this study, we propose a learning-based approach termed CT2X-GAN to synthesize the X-ray images in an end-to-end manner using the content and style disentanglement from three different image domains. Our method decouples the anatomical structure information from CT scans and style information from unpaired real X-ray images/ digital reconstructed radiography (DRR) images via a series of decoupling encoders. Additionally, we introduce a novel consistency regularization term to improve the stylistic resemblance between synthesized X-ray images and real X-ray images. Meanwhile, we also impose a supervised process by computing the similarity of computed real DRR and synthesized DRR images. We further develop a pose attention module to fully strengthen the comprehensive information in the decoupled content code from CT scans, facilitating high-quality multi-view image synthesis in the lower 2D space. Extensive experiments were conducted on the publicly available CTSpine1K dataset and achieved 97.8350, 0.0842 and 3.0938 in terms of FID, KID and defined user-scored X-ray similarity, respectively. In comparison with 3D-aware methods (π-GAN, EG3D), CT2X-GAN is superior in improving the synthesis quality and realistic to the real X-ray images.