# BAHOP: Similarity-based Basin Hopping for A fast hyper-parameter search in WSI classification

arXiv: https://arxiv.org/abs/2404.11161 · HTML: https://mlsanity.com/paper/2404.11161/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 32 references that are in the map.
- First posted on arXiv 17 Apr 2024.

## Builds on (most cited first, 10 of 10)

- [Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images](https://mlsanity.com/paper/2004.09666/) (2020)
- [TransMIL: Transformer based Correlated Multiple Instance Learning for Whole Slide Image Classification](https://mlsanity.com/paper/2106.00908/) (2021)
- [Dual-stream Multiple Instance Learning Network for Whole Slide Image Classification with Self-supervised Contrastive Learning](https://mlsanity.com/paper/2011.08939/) (2020)
- [BOHB: Robust and Efficient Hyperparameter Optimization at Scale](https://mlsanity.com/paper/1807.01774/) (2018)
- [Transfusion: Understanding Transfer Learning for Medical Imaging](https://mlsanity.com/paper/1902.07208/) (2019)
- [DTFD-MIL: Double-Tier Feature Distillation Multiple Instance Learning for Histopathology Whole Slide Image Classification](https://mlsanity.com/paper/2203.12081/) (2022)
- [Quantifying the effects of data augmentation and stain color normalization in convolutional neural networks for computational pathology](https://mlsanity.com/paper/1902.06543/) (2019)
- [Multiple Instance Learning Framework with Masked Hard Instance Mining for Whole Slide Image Classification](https://mlsanity.com/paper/2307.15254/) (2023)
- [Additive MIL: Intrinsically Interpretable Multiple Instance Learning for Pathology](https://mlsanity.com/paper/2206.01794/) (2022)
- [Computational Pathology: A Survey Review and The Way Forward](https://mlsanity.com/paper/2304.05482/) (2023)

## Abstract (arXiv)

Pre-processing whole slide images (WSIs) can impact classification performance. Our study shows that using fixed hyper-parameters for pre-processing out-of-domain WSIs can significantly degrade performance. Therefore, it is critical to search domain-specific hyper-parameters during inference. However, searching for an optimal parameter set is time-consuming. To overcome this, we propose BAHOP, a novel Similarity-based Basin Hopping optimization for fast parameter tuning to enhance inference performance on out-of-domain data. The proposed BAHOP achieves 5% to 30% improvement in accuracy with ×5 times faster on average.