# Enhancing Clinical Efficiency through LLM: Discharge Note Generation for Cardiac Patients

arXiv: https://arxiv.org/abs/2404.05144 · HTML: https://mlsanity.com/paper/2404.05144/

## Key facts

- Cited by 14 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 12 references that are in the map.
- First posted on arXiv 8 Apr 2024.

## Builds on (most cited first, 9 of 9)

- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [TinyLlama: An Open-Source Small Language Model](https://mlsanity.com/paper/2401.02385/) (2024)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [SOLAR 10.7B: Scaling Large Language Models with Simple yet Effective Depth Up-Scaling](https://mlsanity.com/paper/2312.15166/) (2023)
- [Radiology Report Generation with a Learned Knowledge Base and Multi-modal Alignment](https://mlsanity.com/paper/2112.15011/) (2021)
- [Towards Clinical Encounter Summarization: Learning to Compose Discharge Summaries from Prior Notes](https://mlsanity.com/paper/2104.13498/) (2021)

## Built on by (most cited first, 14 of 14)

- [A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directions](https://mlsanity.com/paper/2406.03712/) (2024)
- [MedS3: Towards Medical Slow Thinking with Self-Evolved Soft Dual-sided Process Supervision](https://mlsanity.com/paper/2501.12051/) (2025)
- [ReflecTool: Towards Reflection-Aware Tool-Augmented Clinical Agents](https://mlsanity.com/paper/2410.17657/) (2024)
- [MedTsLLM: Leveraging LLMs for Multimodal Medical Time Series Analysis](https://mlsanity.com/paper/2408.07773/) (2024)
- [Advancing Healthcare Automation: Multi-Agent System for Medical Necessity Justification](https://mlsanity.com/paper/2404.17977/) (2024)
- [AgentEHR: Advancing Autonomous Clinical Decision-Making via Retrospective Summarization](https://mlsanity.com/paper/2601.13918/) (2026)
- [SoK: Privacy-aware LLM in Healthcare: Threat Model, Privacy Techniques, Challenges and Recommendations](https://mlsanity.com/paper/2601.10004/) (2026)
- [Digital Twin Ecosystem for Oncology Clinical Operations](https://mlsanity.com/paper/2409.17650/) (2024)
- [GuidelineGuard: An Agentic Framework for Medical Note Evaluation with Guideline Adherence](https://mlsanity.com/paper/2411.06264/) (2024)
- [Towards Scalable SOAP Note Generation: A Weakly Supervised Multimodal Framework](https://mlsanity.com/paper/2506.10328/) (2025)
- [FASTGEN: Fast and Cost-Effective Synthetic Tabular Data Generation with LLMs](https://mlsanity.com/paper/2507.15839/) (2025)
- [Skin-SOAP: A Weakly Supervised Framework for Generating Structured SOAP Notes](https://mlsanity.com/paper/2508.05019/) (2025)
- [Mitigating Clinician Information Overload: Generative AI for Integrated EHR and RPM Data Analysis](https://mlsanity.com/paper/2509.00073/) (2025)
- [ECG-LLM -- training and evaluation of domain-specific large language models for electrocardiography](https://mlsanity.com/paper/2510.18339/) (2025)

## Abstract (arXiv)

Medical documentation, including discharge notes, is crucial for ensuring patient care quality, continuity, and effective medical communication. However, the manual creation of these documents is not only time-consuming but also prone to inconsistencies and potential errors. The automation of this documentation process using artificial intelligence (AI) represents a promising area of innovation in healthcare. This study directly addresses the inefficiencies and inaccuracies in creating discharge notes manually, particularly for cardiac patients, by employing AI techniques, specifically large language model (LLM). Utilizing a substantial dataset from a cardiology center, encompassing wide-ranging medical records and physician assessments, our research evaluates the capability of LLM to enhance the documentation process. Among the various models assessed, Mistral-7B distinguished itself by accurately generating discharge notes that significantly improve both documentation efficiency and the continuity of care for patients. These notes underwent rigorous qualitative evaluation by medical expert, receiving high marks for their clinical relevance, completeness, readability, and contribution to informed decision-making and care planning. Coupled with quantitative analyses, these results confirm Mistral-7B's efficacy in distilling complex medical information into concise, coherent summaries. Overall, our findings illuminate the considerable promise of specialized LLM, such as Mistral-7B, in refining healthcare documentation workflows and advancing patient care. This study lays the groundwork for further integrating advanced AI technologies in healthcare, demonstrating their potential to revolutionize patient documentation and support better care outcomes.
