# GaSpCT: Gaussian Splatting for Novel CT Projection View Synthesis

arXiv: https://arxiv.org/abs/2404.03126 · HTML: https://mlsanity.com/paper/2404.03126/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 13 of its 24 references that are in the map.
- First posted on arXiv 4 Apr 2024.

## Builds on (most cited first, 13 of 13)

- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [3D Gaussian Splatting for Real-Time Radiance Field Rendering](https://mlsanity.com/paper/2308.04079/) (2023)
- [Mip-NeRF 360: Unbounded Anti-Aliased Neural Radiance Fields](https://mlsanity.com/paper/2111.12077/) (2021)
- [GRAF: Generative Radiance Fields for 3D-Aware Image Synthesis](https://mlsanity.com/paper/2007.02442/) (2020)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [Low Dose CT Image Denoising Using a Generative Adversarial Network with Wasserstein Distance and Perceptual Loss](https://mlsanity.com/paper/1708.00961/) (2017)
- [Framing U-Net via Deep Convolutional Framelets: Application to Sparse-view CT](https://mlsanity.com/paper/1708.08333/) (2017)
- [Nerfbusters: Removing Ghostly Artifacts from Casually Captured NeRFs](https://mlsanity.com/paper/2304.10532/) (2023)
- [MedNeRF: Medical Neural Radiance Fields for Reconstructing 3D-aware CT-Projections from a Single X-ray](https://mlsanity.com/paper/2202.01020/) (2022)
- [Deep-neural-network based sinogram synthesis for sparse-view CT image reconstruction](https://mlsanity.com/paper/1803.00694/) (2018)
- [Fast Auto-Differentiable Digitally Reconstructed Radiographs for Solving Inverse Problems in Intraoperative Imaging](https://mlsanity.com/paper/2208.12737/) (2022)
- [Generative Modeling in Sinogram Domain for Sparse-view CT Reconstruction](https://mlsanity.com/paper/2211.13926/) (2022)
- [Sinogram interpolation for sparse-view micro-CT with deep learning neural network](https://mlsanity.com/paper/1902.03362/) (2019)

## Built on by (most cited first, 6 of 6)

- [R2-Gaussian: Rectifying Radiative Gaussian Splatting for Tomographic Reconstruction](https://mlsanity.com/paper/2405.20693/) (2024)
- [DDGS-CT: Direction-Disentangled Gaussian Splatting for Realistic Volume Rendering](https://mlsanity.com/paper/2406.02518/) (2024)
- [DaRePlane: Direction-aware Representations for Dynamic Scene Reconstruction](https://mlsanity.com/paper/2410.14169/) (2024)
- [A Gaussian Parameterization for Direct Atomic Structure Identification in Electron Tomography](https://mlsanity.com/paper/2512.15034/) (2025)
- [Feed-Forward Hierarchical Gaussian Diffusion for Extreme CT Reconstruction](https://mlsanity.com/paper/2608.15343/) (2026)
- [TR-GS: High-Fidelity Sparse-View CT Volumetric Rendering via t-Distribution Gaussian Splatting and Ray-Confidence Modeling](https://mlsanity.com/paper/2608.16042/) (2026)

## Abstract (arXiv)

We present GaSpCT, a novel view synthesis and 3D scene representation method used to generate novel projection views for Computer Tomography (CT) scans. We adapt the Gaussian Splatting framework to enable novel view synthesis in CT based on limited sets of 2D image projections and without the need for Structure from Motion (SfM) methodologies. Therefore, we reduce the total scanning duration and the amount of radiation dose the patient receives during the scan. We adapted the loss function to our use-case by encouraging a stronger background and foreground distinction using two sparsity promoting regularizers: a beta loss and a total variation (TV) loss. Finally, we initialize the Gaussian locations across the 3D space using a uniform prior distribution of where the brain's positioning would be expected to be within the field of view. We evaluate the performance of our model using brain CT scans from the Parkinson's Progression Markers Initiative (PPMI) dataset and demonstrate that the rendered novel views closely match the original projection views of the simulated scan, and have better performance than other implicit 3D scene representations methodologies. Furthermore, we empirically observe reduced training time compared to neural network based image synthesis for sparse-view CT image reconstruction. Finally, the memory requirements of the Gaussian Splatting representations are reduced by 17% compared to the equivalent voxel grid image representations.