# Adaptive Feature Fusion Neural Network for Glaucoma Segmentation on Unseen Fundus Images

arXiv: https://arxiv.org/abs/2404.02084 · HTML: https://mlsanity.com/paper/2404.02084/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 20 of its 26 references that are in the map.
- First posted on arXiv 2 Apr 2024.

## Builds on (most cited first, 20 of 20)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [mixup: Beyond Empirical Risk Minimization](https://mlsanity.com/paper/1710.09412/) (2017)
- [Parameter-Efficient Transfer Learning for NLP](https://mlsanity.com/paper/1902.00751/) (2019)
- [CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Features](https://mlsanity.com/paper/1905.04899/) (2019)
- [Rethinking Atrous Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1706.05587/) (2017)
- [Making Pre-trained Language Models Better Few-shot Learners](https://mlsanity.com/paper/2012.15723/) (2020)
- [Paying More Attention to Attention: Improving the Performance of Convolutional Neural Networks via Attention Transfer](https://mlsanity.com/paper/1612.03928/) (2016)
- [Deeper, Broader and Artier Domain Generalization](https://mlsanity.com/paper/1710.03077/) (2017)
- [Self-supervised Visual Feature Learning with Deep Neural Networks: A Survey](https://mlsanity.com/paper/1902.06162/) (2019)
- [Domain Generalization via Invariant Feature Representation](https://mlsanity.com/paper/1301.2115/) (2013)
- [Domain Generalization by Solving Jigsaw Puzzles](https://mlsanity.com/paper/1903.06864/) (2019)
- [FedDG: Federated Domain Generalization on Medical Image Segmentation via Episodic Learning in Continuous Frequency Space](https://mlsanity.com/paper/2103.06030/) (2021)
- [REFUGE Challenge: A Unified Framework for Evaluating Automated Methods for Glaucoma Assessment from Fundus Photographs](https://mlsanity.com/paper/1910.03667/) (2019)
- [Deep Self-Learning From Noisy Labels](https://mlsanity.com/paper/1908.02160/) (2019)
- [DoFE: Domain-oriented Feature Embedding for Generalizable Fundus Image Segmentation on Unseen Datasets](https://mlsanity.com/paper/2010.06208/) (2020)
- [Affinity Space Adaptation for Semantic Segmentation Across Domains](https://mlsanity.com/paper/2009.12559/) (2020)
- [Rethinking Domain Generalization Baselines](https://mlsanity.com/paper/2101.09060/) (2021)
- [When Unseen Domain Generalization is Unnecessary? Rethinking Data Augmentation](https://mlsanity.com/paper/1906.03347/) (2019)

## Abstract (arXiv)

Fundus image segmentation on unseen domains is challenging, especially for the over-parameterized deep models trained on the small medical datasets. To address this challenge, we propose a method named Adaptive Feature-fusion Neural Network (AFNN) for glaucoma segmentation on unseen domains, which mainly consists of three modules: domain adaptor, feature-fusion network, and self-supervised multi-task learning. Specifically, the domain adaptor helps the pretrained-model fast adapt from other image domains to the medical fundus image domain. Feature-fusion network and self-supervised multi-task learning for the encoder and decoder are introduced to improve the domain generalization ability. In addition, we also design the weighted-dice-loss to improve model performance on complex optic-cup segmentation tasks. Our proposed method achieves a competitive performance over existing fundus segmentation methods on four public glaucoma datasets.