# Two-Phase Multi-Dose-Level PET Image Reconstruction with Dose Level Awareness

arXiv: https://arxiv.org/abs/2404.01563 · HTML: https://mlsanity.com/paper/2404.01563/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 3 of its 4 references that are in the map.
- First posted on arXiv 2 Apr 2024.

## Builds on (most cited first, 3 of 3)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [FFDNet: Toward a Fast and Flexible Solution for CNN based Image Denoising](https://mlsanity.com/paper/1710.04026/) (2017)
- [Multi-Task Attention-Based Semi-Supervised Learning for Medical Image Segmentation](https://mlsanity.com/paper/1907.12303/) (2019)

## Abstract (arXiv)

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most current methods merely learn the mapping between single-dose-level LPET and SPET images, but omit the dose disparity of LPET images in clinical scenarios. In this paper, to reconstruct high-quality SPET images from multi-dose-level LPET images, we design a novel two-phase multi-dose-level PET reconstruction algorithm with dose level awareness, containing a pre-training phase and a SPET prediction phase. Specifically, the pre-training phase is devised to explore both fine-grained discriminative features and effective semantic representation. The SPET prediction phase adopts a coarse prediction network utilizing pre-learned dose level prior to generate preliminary result, and a refinement network to precisely preserve the details. Experiments on MICCAI 2022 Ultra-low Dose PET Imaging Challenge Dataset have demonstrated the superiority of our method.