# MEDDAP: Medical Dataset Enhancement via Diversified Augmentation Pipeline

arXiv: https://arxiv.org/abs/2403.16335 · HTML: https://mlsanity.com/paper/2403.16335/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 15 of its 29 references that are in the map.
- First posted on arXiv 25 Mar 2024.

## Builds on (most cited first, 15 of 15)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and <0.5MB model size](https://mlsanity.com/paper/1602.07360/) (2016)
- [Intrinsic Dimensionality Explains the Effectiveness of Language Model Fine-Tuning](https://mlsanity.com/paper/2012.13255/) (2020)
- [Medical Diffusion: Denoising Diffusion Probabilistic Models for 3D Medical Image Generation](https://mlsanity.com/paper/2211.03364/) (2022)
- [OOD-CV: A Benchmark for Robustness to Out-of-Distribution Shifts of Individual Nuisances in Natural Images](https://mlsanity.com/paper/2111.14341/) (2021)
- [Sketch guided and progressive growing GAN for realistic and editable ultrasound image synthesis](https://mlsanity.com/paper/2204.06929/) (2022)
- [Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentation](https://mlsanity.com/paper/2305.05424/) (2023)
- [Spot the fake lungs: Generating Synthetic Medical Images using Neural Diffusion Models](https://mlsanity.com/paper/2211.00902/) (2022)
- [Dehazing Ultrasound using Diffusion Models](https://mlsanity.com/paper/2307.11204/) (2023)

## Built on by (most cited first, 2 of 2)

- [Pathology-Aware Adaptive Watermarking for Text-Driven Medical Image Synthesis](https://mlsanity.com/paper/2503.08346/) (2025)
- [SkinDualGen: Prompt-Driven Diffusion for Simultaneous Image-Mask Generation in Skin Lesions](https://mlsanity.com/paper/2507.19970/) (2025)

## Abstract (arXiv)

The effectiveness of Deep Neural Networks (DNNs) heavily relies on the abundance and accuracy of available training data. However, collecting and annotating data on a large scale is often both costly and time-intensive, particularly in medical cases where practitioners are already occupied with their duties. Moreover, ensuring that the model remains robust across various scenarios of image capture is crucial in medical domains, especially when dealing with ultrasound images that vary based on the settings of different devices and the manual operation of the transducer. To address this challenge, we introduce a novel pipeline called MEDDAP, which leverages Stable Diffusion (SD) models to augment existing small datasets by automatically generating new informative labeled samples. Pretrained checkpoints for SD are typically based on natural images, and training them for medical images requires significant GPU resources due to their heavy parameters. To overcome this challenge, we introduce USLoRA (Ultrasound Low-Rank Adaptation), a novel fine-tuning method tailored specifically for ultrasound applications. USLoRA allows for selective fine-tuning of weights within SD, requiring fewer than 0.1% of parameters compared to fully fine-tuning only the UNet portion of SD. To enhance dataset diversity, we incorporate different adjectives into the generation process prompts, thereby desensitizing the classifiers to intensity changes across different images. This approach is inspired by clinicians' decision-making processes regarding breast tumors, where tumor shape often plays a more crucial role than intensity. In conclusion, our pipeline not only outperforms classifiers trained on the original dataset but also demonstrates superior performance when encountering unseen datasets. The source code is available at https://github.com/yasamin-med/MEDDAP.