# Attention-Enhanced Hybrid Feature Aggregation Network for 3D Brain Tumor Segmentation

arXiv: https://arxiv.org/abs/2403.09942 · HTML: https://mlsanity.com/paper/2403.09942/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 11 of its 20 references that are in the map.
- First posted on arXiv 15 Mar 2024.

## Builds on (most cited first, 11 of 11)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [MONAI: An open-source framework for deep learning in healthcare](https://mlsanity.com/paper/2211.02701/) (2022)
- [HiFormer: Hierarchical Multi-scale Representations Using Transformers for Medical Image Segmentation](https://mlsanity.com/paper/2207.08518/) (2022)
- [MedPerf: Open Benchmarking Platform for Medical Artificial Intelligence using Federated Evaluation](https://mlsanity.com/paper/2110.01406/) (2021)
- [MixFormer: Mixing Features across Windows and Dimensions](https://mlsanity.com/paper/2204.02557/) (2022)
- [Deeply-Supervised CNN for Prostate Segmentation](https://mlsanity.com/paper/1703.07523/) (2017)

## Built on by (most cited first, 1 of 1)

- [VEELA: A Clinically-Constrained Benchmark for Liver Vessel Segmentation in Computed Tomography Angiography](https://mlsanity.com/paper/2605.22357/) (2026)

## Abstract (arXiv)

Glioblastoma is a highly aggressive and malignant brain tumor type that requires early diagnosis and prompt intervention. Due to its heterogeneity in appearance, developing automated detection approaches is challenging. To address this challenge, Artificial Intelligence (AI)-driven approaches in healthcare have generated interest in efficiently diagnosing and evaluating brain tumors. The Brain Tumor Segmentation Challenge (BraTS) is a platform for developing and assessing automated techniques for tumor analysis using high-quality, clinically acquired MRI data. In our approach, we utilized a multi-scale, attention-guided and hybrid U-Net-shaped model -- GLIMS -- to perform 3D brain tumor segmentation in three regions: Enhancing Tumor (ET), Tumor Core (TC), and Whole Tumor (WT). The multi-scale feature extraction provides better contextual feature aggregation in high resolutions and the Swin Transformer blocks improve the global feature extraction at deeper levels of the model. The segmentation mask generation in the decoder branch is guided by the attention-refined features gathered from the encoder branch to enhance the important attributes. Moreover, hierarchical supervision is used to train the model efficiently. Our model's performance on the validation set resulted in 92.19, 87.75, and 83.18 Dice Scores and 89.09, 84.67, and 82.15 Lesion-wise Dice Scores in WT, TC, and ET, respectively. The code is publicly available at https://github.com/yaziciz/GLIMS.