# Zero-shot and Few-shot Generation Strategies for Artificial Clinical Records

arXiv: https://arxiv.org/abs/2403.08664 · HTML: https://mlsanity.com/paper/2403.08664/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 10 of its 26 references that are in the map.
- First posted on arXiv 13 Mar 2024.

## Builds on (most cited first, 10 of 10)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Optuna: A Next-generation Hyperparameter Optimization Framework](https://mlsanity.com/paper/1907.10902/) (2019)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [Summarizing Patients Problems from Hospital Progress Notes Using Pre-trained Sequence-to-Sequence Models](https://mlsanity.com/paper/2208.08408/) (2022)
- [Towards Automatic Generation of Shareable Synthetic Clinical Notes Using Neural Language Models](https://mlsanity.com/paper/1905.07002/) (2019)
- [Textual Data Augmentation for Patient Outcomes Prediction](https://mlsanity.com/paper/2211.06778/) (2022)

## Built on by (most cited first, 2 of 2)

- [Language Models Learn Metadata: Political Stance Detection Case Study](https://mlsanity.com/paper/2409.13756/) (2024)
- [Generating Clinical Vignettes that Preserve Cognitive Formulations](https://mlsanity.com/paper/2608.29995/) (2026)

## Abstract (arXiv)

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic medical records that mirror real patient data without compromising individual privacy. The creation of these synthetic datasets, particularly without using actual patient data to train Large Language Models (LLMs), presents a novel solution as gaining access to sensitive patient information to train models is also a challenge. This study assesses the capability of the Llama 2 LLM to create synthetic medical records that accurately reflect real patient information, employing zero-shot and few-shot prompting strategies for comparison against fine-tuned methodologies that do require sensitive patient data during training. We focus on generating synthetic narratives for the History of Present Illness section, utilising data from the MIMIC-IV dataset for comparison. In this work introduce a novel prompting technique that leverages a chain-of-thought approach, enhancing the model's ability to generate more accurate and contextually relevant medical narratives without prior fine-tuning. Our findings suggest that this chain-of-thought prompted approach allows the zero-shot model to achieve results on par with those of fine-tuned models, based on Rouge metrics evaluation.