# Automated Multi-Task Learning for Joint Disease Prediction on Electronic Health Records

arXiv: https://arxiv.org/abs/2403.04086 · HTML: https://mlsanity.com/paper/2403.04086/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 23 of its 38 references that are in the map.
- First posted on arXiv 6 Mar 2024.

## Builds on (most cited first, 23 of 23)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [DARTS: Differentiable Architecture Search](https://mlsanity.com/paper/1806.09055/) (2018)
- [Neural Architecture Search with Reinforcement Learning](https://mlsanity.com/paper/1611.01578/) (2016)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [Regularized Evolution for Image Classifier Architecture Search](https://mlsanity.com/paper/1802.01548/) (2018)
- [ClinicalBERT: Modeling Clinical Notes and Predicting Hospital Readmission](https://mlsanity.com/paper/1904.05342/) (2019)
- [AutoML: A Survey of the State-of-the-Art](https://mlsanity.com/paper/1908.00709/) (2019)
- [Which Tasks Should Be Learned Together in Multi-task Learning?](https://mlsanity.com/paper/1905.07553/) (2019)
- [RETAIN: An Interpretable Predictive Model for Healthcare using Reverse Time Attention Mechanism](https://mlsanity.com/paper/1608.05745/) (2016)
- [Multitask learning and benchmarking with clinical time series data](https://mlsanity.com/paper/1703.07771/) (2017)
- [Efficiently Identifying Task Groupings for Multi-Task Learning](https://mlsanity.com/paper/2109.04617/) (2021)
- [Doctor AI: Predicting Clinical Events via Recurrent Neural Networks](https://mlsanity.com/paper/1511.05942/) (2015)
- [AdaShare: Learning What To Share For Efficient Deep Multi-Task Learning](https://mlsanity.com/paper/1911.12423/) (2019)
- [Dipole: Diagnosis Prediction in Healthcare via Attention-based Bidirectional Recurrent Neural Networks](https://mlsanity.com/paper/1706.05764/) (2017)
- [Learning to Branch for Multi-Task Learning](https://mlsanity.com/paper/2006.01895/) (2020)
- [D-VAE: A Variational Autoencoder for Directed Acyclic Graphs](https://mlsanity.com/paper/1904.11088/) (2019)
- [AdaCare: Explainable Clinical Health Status Representation Learning via Scale-Adaptive Feature Extraction and Recalibration](https://mlsanity.com/paper/1911.12205/) (2019)
- [MTL-NAS: Task-Agnostic Neural Architecture Search towards General-Purpose Multi-Task Learning](https://mlsanity.com/paper/2003.14058/) (2020)
- [Stochastic Filter Groups for Multi-Task CNNs: Learning Specialist and Generalist Convolution Kernels](https://mlsanity.com/paper/1908.09597/) (2019)
- [Deep Elastic Networks with Model Selection for Multi-Task Learning](https://mlsanity.com/paper/1909.04860/) (2019)
- [AutoMTL: A Programming Framework for Automating Efficient Multi-Task Learning](https://mlsanity.com/paper/2110.13076/) (2021)

## Built on by (most cited first, 5 of 5)

- [One Subgoal at a Time: Zero-Shot Generalization to Arbitrary Linear Temporal Logic Requirements in Multi-Task Reinforcement Learning](https://mlsanity.com/paper/2508.01561/) (2025)
- [Tri-MTL: A Triple Multitask Learning Approach for Respiratory Disease Diagnosis](https://mlsanity.com/paper/2505.06271/) (2025)
- [Beyond Traditional Diagnostics: Transforming Patient-Side Information into Predictive Insights with Knowledge Graphs and Prototypes](https://mlsanity.com/paper/2512.08261/) (2025)
- [MiGHT-EHR: A Multi-task Graph Transformer for Heterogeneous Temporal Electronic Health Records](https://mlsanity.com/paper/2608.06430/) (2026)
- [Predicting Multiple Clinical Outcomes Related to Functional Recovery and Social Isolation Among Older Adults After Lower-Limb Fracture or Hip Replacement](https://mlsanity.com/paper/2608.23531/) (2026)

## Abstract (arXiv)

In the realm of big data and digital healthcare, Electronic Health Records (EHR) have become a rich source of information with the potential to improve patient care and medical research. In recent years, machine learning models have proliferated for analyzing EHR data to predict patients future health conditions. Among them, some studies advocate for multi-task learning (MTL) to jointly predict multiple target diseases for improving the prediction performance over single task learning. Nevertheless, current MTL frameworks for EHR data have significant limitations due to their heavy reliance on human experts to identify task groups for joint training and design model architectures. To reduce human intervention and improve the framework design, we propose an automated approach named AutoDP, which can search for the optimal configuration of task grouping and architectures simultaneously. To tackle the vast joint search space encompassing task combinations and architectures, we employ surrogate model-based optimization, enabling us to efficiently discover the optimal solution. Experimental results on real-world EHR data demonstrate the efficacy of the proposed AutoDP framework. It achieves significant performance improvements over both hand-crafted and automated state-of-the-art methods, also maintains a feasible search cost at the same time. Source code can be found via the link: urlhttps://github.com/SH-Src/AutoDP.