# Towards Training A Chinese Large Language Model for Anesthesiology

arXiv: https://arxiv.org/abs/2403.02742 · HTML: https://mlsanity.com/paper/2403.02742/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 24 of its 50 references that are in the map.
- First posted on arXiv 5 Mar 2024.

## Builds on (most cited first, 24 of 24)

- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Constitutional AI: Harmlessness from AI Feedback](https://mlsanity.com/paper/2212.08073/) (2022)
- [Self-Instruct: Aligning Language Models with Self-Generated Instructions](https://mlsanity.com/paper/2212.10560/) (2022)
- [SentencePiece: A simple and language independent subword tokenizer and detokenizer for Neural Text Processing](https://mlsanity.com/paper/1808.06226/) (2018)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [PaLM 2 Technical Report](https://mlsanity.com/paper/2305.10403/) (2023)
- [Large Language Models are not Fair Evaluators](https://mlsanity.com/paper/2305.17926/) (2023)
- [A Diversity-Promoting Objective Function for Neural Conversation Models](https://mlsanity.com/paper/1510.03055/) (2015)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [BloombergGPT: A Large Language Model for Finance](https://mlsanity.com/paper/2303.17564/) (2023)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [Efficient and Effective Text Encoding for Chinese LLaMA and Alpaca](https://mlsanity.com/paper/2304.08177/) (2023)
- [FinGPT: Open-Source Financial Large Language Models](https://mlsanity.com/paper/2306.06031/) (2023)
- [Sparse Upcycling: Training Mixture-of-Experts from Dense Checkpoints](https://mlsanity.com/paper/2212.05055/) (2022)
- [HuaTuo: Tuning LLaMA Model with Chinese Medical Knowledge](https://mlsanity.com/paper/2304.06975/) (2023)
- [DeID-GPT: Zero-shot Medical Text De-Identification by GPT-4](https://mlsanity.com/paper/2303.11032/) (2023)
- [Chatlaw: A Multi-Agent Legal Assistant based on a Role-Aligned Mixture-of-Experts Architecture](https://mlsanity.com/paper/2306.16092/) (2023)
- [Exploring the Impact of Instruction Data Scaling on Large Language Models: An Empirical Study on Real-World Use Cases](https://mlsanity.com/paper/2303.14742/) (2023)
- [Radiology-GPT: A Large Language Model for Radiology](https://mlsanity.com/paper/2306.08666/) (2023)

## Built on by (most cited first, 2 of 2)

- [A Survey for Large Language Models in Biomedicine](https://mlsanity.com/paper/2409.00133/) (2024)
- [AnesSuite: A Comprehensive Benchmark and Dataset Suite for Anesthesiology Reasoning in LLMs](https://mlsanity.com/paper/2504.02404/) (2025)

## Abstract (arXiv)

Medical large language models (LLMs) have gained popularity recently due to their significant practical utility. However, most existing research focuses on general medicine, and there is a need for in-depth study of LLMs in specific fields like anesthesiology. To fill the gap, we introduce Hypnos, a Chinese Anesthesia model built upon existing LLMs, e.g., Llama. Hypnos' contributions have three aspects: 1) The data, such as utilizing Self-Instruct, acquired from current LLMs likely includes inaccuracies. Hypnos implements a cross-filtering strategy to improve the data quality. This strategy involves using one LLM to assess the quality of the generated data from another LLM and filtering out the data with low quality. 2) Hypnos employs a general-to-specific training strategy that starts by fine-tuning LLMs using the general medicine data and subsequently improving the fine-tuned LLMs using data specifically from Anesthesiology. The general medical data supplement the medical expertise in Anesthesiology and enhance the effectiveness of Hypnos' generation. 3) We introduce a standardized benchmark for evaluating medical LLM in Anesthesiology. Our benchmark includes both publicly available instances from the Internet and privately obtained cases from the Hospital. Hypnos outperforms other medical LLMs in anesthesiology in metrics, GPT-4, and human evaluation on the benchmark dataset.