# The Minimum Information about CLinical Artificial Intelligence Checklist for Generative Modeling Research (MI-CLAIM-GEN)

arXiv: https://arxiv.org/abs/2403.02558 · HTML: https://mlsanity.com/paper/2403.02558/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 40 of its 77 references that are in the map.
- First posted on arXiv 5 Mar 2024.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)
- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 30 of 40)

- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Toolformer: Language Models Can Teach Themselves to Use Tools](https://mlsanity.com/paper/2302.04761/) (2023)
- [Lost in the Middle: How Language Models Use Long Contexts](https://mlsanity.com/paper/2307.03172/) (2023)
- [Pre-train, Prompt, and Predict: A Systematic Survey of Prompting Methods in Natural Language Processing](https://mlsanity.com/paper/2107.13586/) (2021)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [Fantastically Ordered Prompts and Where to Find Them: Overcoming Few-Shot Prompt Order Sensitivity](https://mlsanity.com/paper/2104.08786/) (2021)
- [Language Models Don't Always Say What They Think: Unfaithful Explanations in Chain-of-Thought Prompting](https://mlsanity.com/paper/2305.04388/) (2023)
- [Model Cards for Model Reporting](https://mlsanity.com/paper/1810.03993/) (2018)
- [Extracting Training Data from Diffusion Models](https://mlsanity.com/paper/2301.13188/) (2023)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [RLAIF vs. RLHF: Scaling Reinforcement Learning from Human Feedback with AI Feedback](https://mlsanity.com/paper/2309.00267/) (2023)
- [A Survey on Large Language Model (LLM) Security and Privacy: The Good, the Bad, and the Ugly](https://mlsanity.com/paper/2312.02003/) (2023)
- [GPTScore: Evaluate as You Desire](https://mlsanity.com/paper/2302.04166/) (2023)
- [NLP Evaluation in trouble: On the Need to Measure LLM Data Contamination for each Benchmark](https://mlsanity.com/paper/2310.18018/) (2023)
- [Can Generalist Foundation Models Outcompete Special-Purpose Tuning? Case Study in Medicine](https://mlsanity.com/paper/2311.16452/) (2023)
- [State of What Art? A Call for Multi-Prompt LLM Evaluation](https://mlsanity.com/paper/2401.00595/) (2023)
- [How is ChatGPT's behavior changing over time?](https://mlsanity.com/paper/2307.09009/) (2023)
- [Adapted Large Language Models Can Outperform Medical Experts in Clinical Text Summarization](https://mlsanity.com/paper/2309.07430/) (2023)
- [Leak, Cheat, Repeat: Data Contamination and Evaluation Malpractices in Closed-Source LLMs](https://mlsanity.com/paper/2402.03927/) (2024)
- [Navigate through Enigmatic Labyrinth A Survey of Chain of Thought Reasoning: Advances, Frontiers and Future](https://mlsanity.com/paper/2309.15402/) (2023)
- [Repairing the Cracked Foundation: A Survey of Obstacles in Evaluation Practices for Generated Text](https://mlsanity.com/paper/2202.06935/) (2022)
- [From ChatGPT to ThreatGPT: Impact of Generative AI in Cybersecurity and Privacy](https://mlsanity.com/paper/2307.00691/) (2023)
- [Self-Attention Attribution: Interpreting Information Interactions Inside Transformer](https://mlsanity.com/paper/2004.11207/) (2020)
- [Interpreting Language Models with Contrastive Explanations](https://mlsanity.com/paper/2202.10419/) (2022)
- [Are Large Language Model-based Evaluators the Solution to Scaling Up Multilingual Evaluation?](https://mlsanity.com/paper/2309.07462/) (2023)
- [Red-Teaming for Generative AI: Silver Bullet or Security Theater?](https://mlsanity.com/paper/2401.15897/) (2024)
- [Hurtful Words: Quantifying Biases in Clinical Contextual Word Embeddings](https://mlsanity.com/paper/2003.11515/) (2020)
- [Towards Conversational Diagnostic AI](https://mlsanity.com/paper/2401.05654/) (2024)
- [From Understanding to Utilization: A Survey on Explainability for Large Language Models](https://mlsanity.com/paper/2401.12874/) (2024)

## Built on by (most cited first, 3 of 3)

- [textitlucie: An Improved Python Package for Loading Datasets from the UCI Machine Learning Repository](https://mlsanity.com/paper/2410.09119/) (2024)
- [Imaging-anchored multiomics in cardiovascular disease: integrating cardiac imaging, bulk, single-cell, and spatial transcriptomics](https://mlsanity.com/paper/2601.07871/) (2026)
- [RAPTOR+: A Visually Grounded Vision-Language Framework to Improve Clinical Trust and Auditability in Automated Cancer Referral Processing](https://mlsanity.com/paper/2605.25956/) (2026)

## Abstract (arXiv)

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant paradigm shift in how biomedical models can be developed and deployed. While these models are highly adaptable to new tasks, scaling and evaluating their usage presents new challenges not addressed in previous frameworks. In particular, the ability of these models to produce useful outputs with little to no specialized training data ("zero-" or "few-shot" approaches), as well as the open-ended nature of their outputs, necessitate the development of new guidelines for robust reporting of clinical generative model research. In response to gaps in standards and best practices for the development of clinical AI tools identified by US Executive Order 141103 and several emerging national networks for clinical AI evaluation, we begin to formalize some of these guidelines by building on the original MI-CLAIM checklist. The new checklist, MI-CLAIM-GEN (Table 1), aims to address differences in training, evaluation, interpretability, and reproducibility of new generative models compared to non-generative ("predictive") AI models. This MI-CLAIM-GEN checklist also seeks to clarify cohort selection reporting with unstructured clinical data and adds additional items on alignment with ethical standards for clinical AI research.