# Objective and Interpretable Breast Cosmesis Evaluation with Attention Guided Denoising Diffusion Anomaly Detection Model

arXiv: https://arxiv.org/abs/2402.18362 · HTML: https://mlsanity.com/paper/2402.18362/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 27 of its 48 references that are in the map.
- First posted on arXiv 28 Feb 2024.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 27 of 27)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Auto-Encoding Variational Bayes](https://mlsanity.com/paper/1312.6114/) (2013)
- [SDEdit: Guided Image Synthesis and Editing with Stochastic Differential Equations](https://mlsanity.com/paper/2108.01073/) (2021)
- [Towards Total Recall in Industrial Anomaly Detection](https://mlsanity.com/paper/2106.08265/) (2021)
- [PaDiM: a Patch Distribution Modeling Framework for Anomaly Detection and Localization](https://mlsanity.com/paper/2011.08785/) (2020)
- [DRAEM -- A discriminatively trained reconstruction embedding for surface anomaly detection](https://mlsanity.com/paper/2108.07610/) (2021)
- [Anomaly Detection via Reverse Distillation from One-Class Embedding](https://mlsanity.com/paper/2201.10703/) (2022)
- [GANomaly: Semi-Supervised Anomaly Detection via Adversarial Training](https://mlsanity.com/paper/1805.06725/) (2018)
- [Deep Learning for Anomaly Detection: A Survey](https://mlsanity.com/paper/1901.03407/) (2019)
- [Deep ViT Features as Dense Visual Descriptors](https://mlsanity.com/paper/2112.05814/) (2021)
- [Sub-Image Anomaly Detection with Deep Pyramid Correspondences](https://mlsanity.com/paper/2005.02357/) (2020)
- [FastFlow: Unsupervised Anomaly Detection and Localization via 2D Normalizing Flows](https://mlsanity.com/paper/2111.07677/) (2021)
- [Student-Teacher Feature Pyramid Matching for Anomaly Detection](https://mlsanity.com/paper/2103.04257/) (2021)
- [CFA: Coupled-hypersphere-based Feature Adaptation for Target-Oriented Anomaly Localization](https://mlsanity.com/paper/2206.04325/) (2022)
- [Fully Convolutional Cross-Scale-Flows for Image-based Defect Detection](https://mlsanity.com/paper/2110.02855/) (2021)
- [An Analysis of Deep Neural Network Models for Practical Applications](https://mlsanity.com/paper/1605.07678/) (2016)
- [Deep Nearest Neighbor Anomaly Detection](https://mlsanity.com/paper/2002.10445/) (2020)
- [Anomaly Detection with Conditioned Denoising Diffusion Models](https://mlsanity.com/paper/2305.15956/) (2023)
- [A Close Look at Deep Learning with Small Data](https://mlsanity.com/paper/2003.12843/) (2020)
- [Mask, Stitch, and Re-Sample: Enhancing Robustness and Generalizability in Anomaly Detection through Automatic Diffusion Models](https://mlsanity.com/paper/2305.19643/) (2023)
- [Dynamic Fusion Module Evolves Drivable Area and Road Anomaly Detection: A Benchmark and Algorithms](https://mlsanity.com/paper/2103.02433/) (2021)
- [A Tour of Unsupervised Deep Learning for Medical Image Analysis](https://mlsanity.com/paper/1812.07715/) (2018)

## Abstract (arXiv)

As advancements in the field of breast cancer treatment continue to progress, the assessment of post-surgical cosmetic outcomes has gained increasing significance due to its substantial impact on patients' quality of life. However, evaluating breast cosmesis presents challenges due to the inherently subjective nature of expert labeling. In this study, we present a novel automated approach, Attention-Guided Denoising Diffusion Anomaly Detection (AG-DDAD), designed to assess breast cosmesis following surgery, addressing the limitations of conventional supervised learning and existing anomaly detection models. Our approach leverages the attention mechanism of the distillation with no label (DINO) self-supervised Vision Transformer (ViT) in combination with a diffusion model to achieve high-quality image reconstruction and precise transformation of discriminative regions. By training the diffusion model on unlabeled data predominantly with normal cosmesis, we adopt an unsupervised anomaly detection perspective to automatically score the cosmesis. Real-world data experiments demonstrate the effectiveness of our method, providing visually appealing representations and quantifiable scores for cosmesis evaluation. Compared to commonly used rule-based programs, our fully automated approach eliminates the need for manual annotations and offers objective evaluation. Moreover, our anomaly detection model exhibits state-of-the-art performance, surpassing existing models in accuracy. Going beyond the scope of breast cosmesis, our research represents a significant advancement in unsupervised anomaly detection within the medical domain, thereby paving the way for future investigations.