# Constraint Latent Space Matters: An Anti-anomalous Waveform Transformation Solution from Photoplethysmography to Arterial Blood Pressure

arXiv: https://arxiv.org/abs/2402.17780 · HTML: https://mlsanity.com/paper/2402.17780/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 19 of its 53 references that are in the map.
- First posted on arXiv 23 Feb 2024.

## Builds on (most cited first, 19 of 19)

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- [CardioGAN: Attentive Generative Adversarial Network with Dual Discriminators for Synthesis of ECG from PPG](https://mlsanity.com/paper/2010.00104/) (2020)
- [Style Transfer for Anime Sketches with Enhanced Residual U-net and Auxiliary Classifier GAN](https://mlsanity.com/paper/1706.03319/) (2017)
- [TTS-CGAN: A Transformer Time-Series Conditional GAN for Biosignal Data Augmentation](https://mlsanity.com/paper/2206.13676/) (2022)
- [PPG2ABP: Translating Photoplethysmogram (PPG) Signals to Arterial Blood Pressure (ABP) Waveforms using Fully Convolutional Neural Networks](https://mlsanity.com/paper/2005.01669/) (2020)
- [Domain Adaptation Meets Zero-Shot Learning: An Annotation-Efficient Approach to Multi-Modality Medical Image Segmentation](https://mlsanity.com/paper/2203.10332/) (2022)
- [Performer: A Novel PPG-to-ECG Reconstruction Transformer for a Digital Biomarker of Cardiovascular Disease Detection](https://mlsanity.com/paper/2204.11795/) (2022)
- [Estimation of Continuous Blood Pressure from PPG via a Federated Learning Approach](https://mlsanity.com/paper/2102.12245/) (2021)
- [All Grains, One Scheme (AGOS): Learning Multi-grain Instance Representation for Aerial Scene Classification](https://mlsanity.com/paper/2205.03371/) (2022)
- [BP-Net: Efficient Deep Learning for Continuous Arterial Blood Pressure Estimation using Photoplethysmogram](https://mlsanity.com/paper/2111.14558/) (2021)

## Abstract (arXiv)

Arterial blood pressure (ABP) holds substantial promise for proactive cardiovascular health management. Notwithstanding its potential, the invasive nature of ABP measurements confines their utility primarily to clinical environments, limiting their applicability for continuous monitoring beyond medical facilities. The conversion of photoplethysmography (PPG) signals into ABP equivalents has garnered significant attention due to its potential in revolutionizing cardiovascular disease management. Recent strides in PPG-to-ABP prediction encompass the integration of generative and discriminative models. Despite these advances, the efficacy of these models is curtailed by the latent space shift predicament, stemming from alterations in PPG data distribution across disparate hardware and individuals, potentially leading to distorted ABP waveforms. To tackle this problem, we present an innovative solution named the Latent Space Constraint Transformer (LSCT), leveraging a quantized codebook to yield robust latent spaces by employing multiple discretizing bases. To facilitate improved reconstruction, the Correlation-boosted Attention Module (CAM) is introduced to systematically query pertinent bases on a global scale. Furthermore, to enhance expressive capacity, we propose the Multi-Spectrum Enhancement Knowledge (MSEK), which fosters local information flow within the channels of latent code and provides additional embedding for reconstruction. Through comprehensive experimentation on both publicly available datasets and a private downstream task dataset, the proposed approach demonstrates noteworthy performance enhancements compared to existing methods. Extensive ablation studies further substantiate the effectiveness of each introduced module.