# Towards Building Multilingual Language Model for Medicine

arXiv: https://arxiv.org/abs/2402.13963 · HTML: https://mlsanity.com/paper/2402.13963/

## Key facts

- Cited by 92 papers in the map (data through 14 Oct 2026).
- Builds on 38 of its 56 references that are in the map.
- First posted on arXiv 21 Feb 2024.

## Builds on (most cited first, 30 of 38)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Scaling Laws for Neural Language Models](https://mlsanity.com/paper/2001.08361/) (2020)
- [Self-Consistency Improves Chain of Thought Reasoning in Language Models](https://mlsanity.com/paper/2203.11171/) (2022)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [Mistral 7B](https://mlsanity.com/paper/2310.06825/) (2023)
- [Scaling Instruction-Finetuned Language Models](https://mlsanity.com/paper/2210.11416/) (2022)
- [BLOOM: A 176B-Parameter Open-Access Multilingual Language Model](https://mlsanity.com/paper/2211.05100/) (2022)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Exams](https://mlsanity.com/paper/2009.13081/) (2020)
- [PubMedQA: A Dataset for Biomedical Research Question Answering](https://mlsanity.com/paper/1909.06146/) (2019)
- [PaLM 2 Technical Report](https://mlsanity.com/paper/2305.10403/) (2023)
- [Super-NaturalInstructions: Generalization via Declarative Instructions on 1600+ NLP Tasks](https://mlsanity.com/paper/2204.07705/) (2022)
- [The Flan Collection: Designing Data and Methods for Effective Instruction Tuning](https://mlsanity.com/paper/2301.13688/) (2023)
- [MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answering](https://mlsanity.com/paper/2203.14371/) (2022)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [Can Generalist Foundation Models Outcompete Special-Purpose Tuning? Case Study in Medicine](https://mlsanity.com/paper/2311.16452/) (2023)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domains](https://mlsanity.com/paper/2402.10373/) (2024)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [MEDITRON-70B: Scaling Medical Pretraining for Large Language Models](https://mlsanity.com/paper/2311.16079/) (2023)
- [Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Data](https://mlsanity.com/paper/2308.02463/) (2023)
- [CulturaX: A Cleaned, Enormous, and Multilingual Dataset for Large Language Models in 167 Languages](https://mlsanity.com/paper/2309.09400/) (2023)

## Built on by (most cited first, 30 of 92)

- [MedReason: Eliciting Factual Medical Reasoning Steps in LLMs via Knowledge Graphs](https://mlsanity.com/paper/2504.00993/) (2025)
- [A Comprehensive Survey of Scientific Large Language Models and Their Applications in Scientific Discovery](https://mlsanity.com/paper/2406.10833/) (2024)
- [RaTEScore: A Metric for Radiology Report Generation](https://mlsanity.com/paper/2406.16845/) (2024)
- [MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks](https://mlsanity.com/paper/2505.23802/) (2025)
- [m1: Unleash the Potential of Test-Time Scaling for Medical Reasoning with Large Language Models](https://mlsanity.com/paper/2504.00869/) (2025)
- [Towards Evaluating and Building Versatile Large Language Models for Medicine](https://mlsanity.com/paper/2408.12547/) (2024)
- [Apollo: A Lightweight Multilingual Medical LLM towards Democratizing Medical AI to 6B People](https://mlsanity.com/paper/2403.03640/) (2024)
- [O1 Replication Journey -- Part 3: Inference-time Scaling for Medical Reasoning](https://mlsanity.com/paper/2501.06458/) (2025)
- [ClinicalLab: Aligning Agents for Multi-Departmental Clinical Diagnostics in the Real World](https://mlsanity.com/paper/2406.13890/) (2024)
- [MEDDxAgent: A Unified Modular Agent Framework for Explainable Automatic Differential Diagnosis](https://mlsanity.com/paper/2502.19175/) (2025)
- [Aloe: A Family of Fine-tuned Open Healthcare LLMs](https://mlsanity.com/paper/2405.01886/) (2024)
- [Medchain: Bridging the Gap Between LLM Agents and Clinical Practice with Interactive Sequence](https://mlsanity.com/paper/2412.01605/) (2024)
- [A Survey on Large Language Models from General Purpose to Medical Applications: Datasets, Methodologies, and Evaluations](https://mlsanity.com/paper/2406.10303/) (2024)
- [MedArabiQ: Benchmarking Large Language Models on Arabic Medical Tasks](https://mlsanity.com/paper/2505.03427/) (2025)
- [Multimodal Medical Code Tokenizer](https://mlsanity.com/paper/2502.04397/) (2025)
- [Graphusion: A RAG Framework for Knowledge Graph Construction with a Global Perspective](https://mlsanity.com/paper/2410.17600/) (2024)
- [BRIDGE: Benchmarking Large Language Models for Understanding Real-world Clinical Practice Text](https://mlsanity.com/paper/2504.19467/) (2025)
- [CLINIC: Evaluating Multilingual Trustworthiness in Language Models for Healthcare](https://mlsanity.com/paper/2512.11437/) (2025)
- [TAIA: Large Language Models are Out-of-Distribution Data Learners](https://mlsanity.com/paper/2405.20192/) (2024)
- [FEDMEKI: A Benchmark for Scaling Medical Foundation Models via Federated Knowledge Injection](https://mlsanity.com/paper/2408.09227/) (2024)
- [JMedBench: A Benchmark for Evaluating Japanese Biomedical Large Language Models](https://mlsanity.com/paper/2409.13317/) (2024)
- [From Text to Multimodality: Exploring the Evolution and Impact of Large Language Models in Medical Practice](https://mlsanity.com/paper/2410.01812/) (2024)
- [MING-MOE: Enhancing Medical Multi-Task Learning in Large Language Models with Sparse Mixture of Low-Rank Adapter Experts](https://mlsanity.com/paper/2404.09027/) (2024)
- [Unleashing the Potential of Vision-Language Pre-Training for 3D Zero-Shot Lesion Segmentation via Mask-Attribute Alignment](https://mlsanity.com/paper/2410.15744/) (2024)
- [Structure-aware Domain Knowledge Injection for Large Language Models](https://mlsanity.com/paper/2407.16724/) (2024)
- [Performance Evaluation of Large Language Models in Bangla Consumer Health Query Summarization](https://mlsanity.com/paper/2505.05070/) (2025)
- [Alleviating Textual Reliance in Medical Language-guided Segmentation via Prototype-driven Semantic Approximation](https://mlsanity.com/paper/2507.11055/) (2025)
- [FEDKIM: Adaptive Federated Knowledge Injection into Medical Foundation Models](https://mlsanity.com/paper/2408.10276/) (2024)
- [Knowledge Hierarchy Guided Biological-Medical Dataset Distillation for Domain LLM Training](https://mlsanity.com/paper/2501.15108/) (2025)
- [From large language models to multimodal AI: A scoping review on the potential of generative AI in medicine](https://mlsanity.com/paper/2502.09242/) (2025)

## Abstract (arXiv)

The development of open-source, multilingual medical language models can benefit a wide, linguistically diverse audience from different regions. To promote this domain, we present contributions from the following: First, we construct a multilingual medical corpus, containing approximately 25.5B tokens encompassing 6 main languages, termed as MMedC, enabling auto-regressive domain adaptation for general LLMs; Second, to monitor the development of multilingual medical LLMs, we propose a multilingual medical multi-choice question-answering benchmark with rationale, termed as MMedBench; Third, we have assessed a number of open-source large language models (LLMs) on our benchmark, along with those further auto-regressive trained on MMedC. Our final model, MMed-Llama 3, with only 8B parameters, achieves superior performance compared to all other open-source models on both MMedBench and English benchmarks, even rivaling GPT-4. In conclusion, in this work, we present a large-scale corpus, a benchmark and a series of models to support the development of multilingual medical LLMs.