# DeepATLAS: One-Shot Localization for Biomedical Data

arXiv: https://arxiv.org/abs/2402.09587 · HTML: https://mlsanity.com/paper/2402.09587/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 20 of its 48 references that are in the map.
- First posted on arXiv 14 Feb 2024.

## Builds on (most cited first, 20 of 20)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Unsupervised Representation Learning with Deep Convolutional Generative Adversarial Networks](https://mlsanity.com/paper/1511.06434/) (2015)
- [Identity Mappings in Deep Residual Networks](https://mlsanity.com/paper/1603.05027/) (2016)
- [Group Normalization](https://mlsanity.com/paper/1803.08494/) (2018)
- [Unsupervised Learning of Visual Representations by Solving Jigsaw Puzzles](https://mlsanity.com/paper/1603.09246/) (2016)
- [On the Variance of the Adaptive Learning Rate and Beyond](https://mlsanity.com/paper/1908.03265/) (2019)
- [VoxelMorph: A Learning Framework for Deformable Medical Image Registration](https://mlsanity.com/paper/1809.05231/) (2018)
- [TotalSegmentator: robust segmentation of 104 anatomical structures in CT images](https://mlsanity.com/paper/2208.05868/) (2022)
- [One-Shot Learning for Semantic Segmentation](https://mlsanity.com/paper/1709.03410/) (2017)
- [Segment Anything Model for Medical Image Analysis: an Experimental Study](https://mlsanity.com/paper/2304.10517/) (2023)
- [A review of deep learning in medical imaging: Imaging traits, technology trends, case studies with progress highlights, and future promises](https://mlsanity.com/paper/2008.09104/) (2020)
- [AbdomenCT-1K: Is Abdominal Organ Segmentation A Solved Problem?](https://mlsanity.com/paper/2010.14808/) (2020)
- [SG-One: Similarity Guidance Network for One-Shot Semantic Segmentation](https://mlsanity.com/paper/1810.09091/) (2018)
- [A Survey on Active Learning and Human-in-the-Loop Deep Learning for Medical Image Analysis](https://mlsanity.com/paper/1910.02923/) (2019)
- [Deep Learning for Medical Anomaly Detection -- A Survey](https://mlsanity.com/paper/2012.02364/) (2020)
- [Deep Learning in Medical Image Registration: A Review](https://mlsanity.com/paper/1912.12318/) (2019)
- [Deep learning to achieve clinically applicable segmentation of head and neck anatomy for radiotherapy](https://mlsanity.com/paper/1809.04430/) (2018)
- [Deep Learning-Based Regression and Classification for Automatic Landmark Localization in Medical Images](https://mlsanity.com/paper/2007.05295/) (2020)
- [An Empirical Review of Deep Learning Frameworks for Change Detection: Model Design, Experimental Frameworks, Challenges and Research Needs](https://mlsanity.com/paper/2105.01342/) (2021)

## Abstract (arXiv)

This paper introduces the DeepATLAS foundational model for localization tasks in the domain of high-dimensional biomedical data. Upon convergence of the proposed self-supervised objective, a pretrained model maps an input to an anatomically-consistent embedding from which any point or set of points (e.g., boxes or segmentations) may be identified in a one-shot or few-shot approach. As a representative benchmark, a DeepATLAS model pretrained on a comprehensive cohort of 51,000+ unlabeled 3D computed tomography exams yields high one-shot segmentation performance on over 50 anatomic structures across four different external test sets, either matching or exceeding the performance of a standard supervised learning model. Further improvements in accuracy can be achieved by adding a small amount of labeled data using either a semisupervised or more conventional fine-tuning strategy.