# OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM

arXiv: https://arxiv.org/abs/2402.09181 · HTML: https://mlsanity.com/paper/2402.09181/

## Key facts

- Cited by 184 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 54 of its 128 references that are in the map.
- First posted on arXiv 14 Feb 2024.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)

## Builds on (most cited first, 30 of 54)

- [Training language models to follow instructions with human feedback](https://mlsanity.com/paper/2203.02155/) (2022)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Visual Instruction Tuning](https://mlsanity.com/paper/2304.08485/) (2023)
- [BLIP-2: Bootstrapping Language-Image Pre-training with Frozen Image Encoders and Large Language Models](https://mlsanity.com/paper/2301.12597/) (2023)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [InstructBLIP: Towards General-purpose Vision-Language Models with Instruction Tuning](https://mlsanity.com/paper/2305.06500/) (2023)
- [MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Models](https://mlsanity.com/paper/2304.10592/) (2023)
- [Visual Genome: Connecting Language and Vision Using Crowdsourced Dense Image Annotations](https://mlsanity.com/paper/1602.07332/) (2016)
- [LAION-400M: Open Dataset of CLIP-Filtered 400 Million Image-Text Pairs](https://mlsanity.com/paper/2111.02114/) (2021)
- [Microsoft COCO Captions: Data Collection and Evaluation Server](https://mlsanity.com/paper/1504.00325/) (2015)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [Conceptual 12M: Pushing Web-Scale Image-Text Pre-Training To Recognize Long-Tail Visual Concepts](https://mlsanity.com/paper/2102.08981/) (2021)
- [mPLUG-Owl: Modularization Empowers Large Language Models with Multimodality](https://mlsanity.com/paper/2304.14178/) (2023)
- [Instruction Tuning with GPT-4](https://mlsanity.com/paper/2304.03277/) (2023)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [LLaMA-Adapter V2: Parameter-Efficient Visual Instruction Model](https://mlsanity.com/paper/2304.15010/) (2023)
- [Otter: A Multi-Modal Model with In-Context Instruction Tuning](https://mlsanity.com/paper/2305.03726/) (2023)
- [Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1710.05006/) (2017)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [DriveGPT4: Interpretable End-to-end Autonomous Driving via Large Language Model](https://mlsanity.com/paper/2310.01412/) (2023)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Med-Flamingo: a Multimodal Medical Few-shot Learner](https://mlsanity.com/paper/2307.15189/) (2023)
- [AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentation](https://mlsanity.com/paper/2206.08023/) (2022)
- [PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answering](https://mlsanity.com/paper/2305.10415/) (2023)
- [GeoChat: Grounded Large Vision-Language Model for Remote Sensing](https://mlsanity.com/paper/2311.15826/) (2023)
- [EmbodiedGPT: Vision-Language Pre-Training via Embodied Chain of Thought](https://mlsanity.com/paper/2305.15021/) (2023)
- [COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images](https://mlsanity.com/paper/2003.09871/) (2020)
- [REFUGE Challenge: A Unified Framework for Evaluating Automated Methods for Glaucoma Assessment from Fundus Photographs](https://mlsanity.com/paper/1910.03667/) (2019)
- [LVLM-eHub: A Comprehensive Evaluation Benchmark for Large Vision-Language Models](https://mlsanity.com/paper/2306.09265/) (2023)

## Built on by (most cited first, 30 of 184)

- [MMAU: A Massive Multi-Task Audio Understanding and Reasoning Benchmark](https://mlsanity.com/paper/2410.19168/) (2024)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale](https://mlsanity.com/paper/2406.19280/) (2024)
- [MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via Reinforcement Learning](https://mlsanity.com/paper/2502.19634/) (2025)
- [Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Models](https://mlsanity.com/paper/2503.13939/) (2025)
- [HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptation](https://mlsanity.com/paper/2502.09838/) (2025)
- [PyVision: Agentic Vision with Dynamic Tooling](https://mlsanity.com/paper/2507.07998/) (2025)
- [VL-Uncertainty: Detecting Hallucination in Large Vision-Language Model via Uncertainty Estimation](https://mlsanity.com/paper/2411.11919/) (2024)
- [Ming-Omni: A Unified Multimodal Model for Perception and Generation](https://mlsanity.com/paper/2506.09344/) (2025)
- [CARES: A Comprehensive Benchmark of Trustworthiness in Medical Vision Language Models](https://mlsanity.com/paper/2406.06007/) (2024)
- [LLM Agents for Education: Advances and Applications](https://mlsanity.com/paper/2503.11733/) (2025)
- [VILA-M3: Enhancing Vision-Language Models with Medical Expert Knowledge](https://mlsanity.com/paper/2411.12915/) (2024)
- [PhD: A ChatGPT-Prompted Visual hallucination Evaluation Dataset](https://mlsanity.com/paper/2403.11116/) (2024)
- [MMedAgent-RL: Optimizing Multi-Agent Collaboration for Multimodal Medical Reasoning](https://mlsanity.com/paper/2506.00555/) (2025)
- [A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers](https://mlsanity.com/paper/2508.21148/) (2025)
- [X-Reasoner: Towards Generalizable Reasoning Across Modalities and Domains](https://mlsanity.com/paper/2505.03981/) (2025)
- [GEMeX: A Large-Scale, Groundable, and Explainable Medical VQA Benchmark for Chest X-ray Diagnosis](https://mlsanity.com/paper/2411.16778/) (2024)
- [Towards a Multimodal Large Language Model with Pixel-Level Insight for Biomedicine](https://mlsanity.com/paper/2412.09278/) (2024)
- [Pillar-0: A New Frontier for Radiology Foundation Models](https://mlsanity.com/paper/2511.17803/) (2025)
- [GMAI-VL & GMAI-VL-5.5M: A Large Vision-Language Model and A Comprehensive Multimodal Dataset Towards General Medical AI](https://mlsanity.com/paper/2411.14522/) (2024)
- [MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation models](https://mlsanity.com/paper/2409.15477/) (2024)
- [STLLaVA-Med: Self-Training Large Language and Vision Assistant for Medical Question-Answering](https://mlsanity.com/paper/2406.19973/) (2024)
- [MedBench: A Comprehensive, Standardized, and Reliable Benchmarking System for Evaluating Chinese Medical Large Language Models](https://mlsanity.com/paper/2407.10990/) (2024)
- [Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey](https://mlsanity.com/paper/2408.12880/) (2024)
- [Redundancy Principles for MLLMs Benchmarks](https://mlsanity.com/paper/2501.13953/) (2025)
- [Towards Better Dental AI: A Multimodal Benchmark and Instruction Dataset for Panoramic X-ray Analysis](https://mlsanity.com/paper/2509.09254/) (2025)
- [A Spectrum Evaluation Benchmark for Medical Multi-Modal Large Language Models](https://mlsanity.com/paper/2402.11217/) (2024)
- [Multimodal Large Language Models for Medicine: A Comprehensive Survey](https://mlsanity.com/paper/2504.21051/) (2025)
- [Show Me What and Where has Changed? Question Answering and Grounding for Remote Sensing Change Detection](https://mlsanity.com/paper/2410.23828/) (2024)

## Abstract (arXiv)

Large Vision-Language Models (LVLMs) have demonstrated remarkable capabilities in various multimodal tasks. However, their potential in the medical domain remains largely unexplored. A significant challenge arises from the scarcity of diverse medical images spanning various modalities and anatomical regions, which is essential in real-world medical applications. To solve this problem, in this paper, we introduce OmniMedVQA, a novel comprehensive medical Visual Question Answering (VQA) benchmark. This benchmark is collected from 73 different medical datasets, including 12 different modalities and covering more than 20 distinct anatomical regions. Importantly, all images in this benchmark are sourced from authentic medical scenarios, ensuring alignment with the requirements of the medical field and suitability for evaluating LVLMs. Through our extensive experiments, we have found that existing LVLMs struggle to address these medical VQA problems effectively. Moreover, what surprises us is that medical-specialized LVLMs even exhibit inferior performance to those general-domain models, calling for a more versatile and robust LVLM in the biomedical field. The evaluation results not only reveal the current limitations of LVLM in understanding real medical images but also highlight our dataset's significance. Our code with dataset are available at https://github.com/OpenGVLab/Multi-Modality-Arena.