# Adversarially Robust Feature Learning for Breast Cancer Diagnosis

arXiv: https://arxiv.org/abs/2402.08768 · HTML: https://mlsanity.com/paper/2402.08768/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 32 of its 42 references that are in the map.
- First posted on arXiv 13 Feb 2024.

## Builds on (most cited first, 30 of 32)

- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Explaining and Harnessing Adversarial Examples](https://mlsanity.com/paper/1412.6572/) (2014)
- [Towards Deep Learning Models Resistant to Adversarial Attacks](https://mlsanity.com/paper/1706.06083/) (2017)
- [Intriguing properties of neural networks](https://mlsanity.com/paper/1312.6199/) (2013)
- [Theoretically Principled Trade-off between Robustness and Accuracy](https://mlsanity.com/paper/1901.08573/) (2019)
- [Adversarial Examples Are Not Bugs, They Are Features](https://mlsanity.com/paper/1905.02175/) (2019)
- [Adversarial Machine Learning at Scale](https://mlsanity.com/paper/1611.01236/) (2016)
- [Virtual Adversarial Training: A Regularization Method for Supervised and Semi-Supervised Learning](https://mlsanity.com/paper/1704.03976/) (2017)
- [Robustness May Be at Odds with Accuracy](https://mlsanity.com/paper/1805.12152/) (2018)
- [Adversarial Training for Free!](https://mlsanity.com/paper/1904.12843/) (2019)
- [Overfitting in adversarially robust deep learning](https://mlsanity.com/paper/2002.11569/) (2020)
- [Adversarial Examples Improve Image Recognition](https://mlsanity.com/paper/1911.09665/) (2019)
- [Domain-Specific Batch Normalization for Unsupervised Domain Adaptation](https://mlsanity.com/paper/1906.03950/) (2019)
- [Understanding Adversarial Attacks on Deep Learning Based Medical Image Analysis Systems](https://mlsanity.com/paper/1907.10456/) (2019)
- [Understanding and Mitigating the Tradeoff Between Robustness and Accuracy](https://mlsanity.com/paper/2002.10716/) (2020)
- [Adversarial Training Can Hurt Generalization](https://mlsanity.com/paper/1906.06032/) (2019)
- [Feature Purification: How Adversarial Training Performs Robust Deep Learning](https://mlsanity.com/paper/2005.10190/) (2020)
- [Recent advances and clinical applications of deep learning in medical image analysis](https://mlsanity.com/paper/2105.13381/) (2021)
- [Interpreting Adversarially Trained Convolutional Neural Networks](https://mlsanity.com/paper/1905.09797/) (2019)
- [Improving the Generalization of Adversarial Training with Domain Adaptation](https://mlsanity.com/paper/1810.00740/) (2018)
- [Dual Manifold Adversarial Robustness: Defense against Lp and non-Lp Adversarial Attacks](https://mlsanity.com/paper/2009.02470/) (2020)
- [A Survey of Robust Adversarial Training in Pattern Recognition: Fundamental, Theory, and Methodologies](https://mlsanity.com/paper/2203.14046/) (2022)
- [A Unified Gradient Regularization Family for Adversarial Examples](https://mlsanity.com/paper/1511.06385/) (2015)
- [CT-GAN: Malicious Tampering of 3D Medical Imagery using Deep Learning](https://mlsanity.com/paper/1901.03597/) (2019)
- [Robust breast cancer detection in mammography and digital breast tomosynthesis using annotation-efficient deep learning approach](https://mlsanity.com/paper/1912.11027/) (2019)
- [Miss the Point: Targeted Adversarial Attack on Multiple Landmark Detection](https://mlsanity.com/paper/2007.05225/) (2020)
- [Adversarial Robustness via Fisher-Rao Regularization](https://mlsanity.com/paper/2106.06685/) (2021)
- [Survey on Adversarial Attack and Defense for Medical Image Analysis: Methods and Challenges](https://mlsanity.com/paper/2303.14133/) (2023)
- [Why adversarial training can hurt robust accuracy](https://mlsanity.com/paper/2203.02006/) (2022)
- [Advancing diagnostic performance and clinical usability of neural networks via adversarial training and dual batch normalization](https://mlsanity.com/paper/2011.13011/) (2020)

## Built on by (most cited first, 3 of 3)

- [Prompt2Perturb (P2P): Text-Guided Diffusion-Based Adversarial Attacks on Breast Ultrasound Images](https://mlsanity.com/paper/2412.09910/) (2024)
- [RCDM: Enabling Robustness for Conditional Diffusion Model](https://mlsanity.com/paper/2408.02710/) (2024)
- [Cross-Attention Multimodal Fusion for Breast Cancer Diagnosis: Integrating Mammography and Clinical Data with Explainability](https://mlsanity.com/paper/2508.16000/) (2025)

## Abstract (arXiv)

Adversarial data can lead to malfunction of deep learning applications. It is essential to develop deep learning models that are robust to adversarial data while accurate on standard, clean data. In this study, we proposed a novel adversarially robust feature learning (ARFL) method for a real-world application of breast cancer diagnosis. ARFL facilitates adversarial training using both standard data and adversarial data, where a feature correlation measure is incorporated as an objective function to encourage learning of robust features and restrain spurious features. To show the effects of ARFL in breast cancer diagnosis, we built and evaluated diagnosis models using two independent clinically collected breast imaging datasets, comprising a total of 9,548 mammogram images. We performed extensive experiments showing that our method outperformed several state-of-the-art methods and that our method can enhance safer breast cancer diagnosis against adversarial attacks in clinical settings.
