# P-Mamba: Marrying Perona Malik Diffusion with Mamba for Efficient Pediatric Echocardiographic Left Ventricular Segmentation

arXiv: https://arxiv.org/abs/2402.08506 · HTML: https://mlsanity.com/paper/2402.08506/

## Key facts

- Cited by 21 papers in the map (data through 14 Oct 2026).
- Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba).
- Builds on 14 of its 27 references that are in the map.
- First posted on arXiv 13 Feb 2024.

## Placed in

- State-space sequence models (S4, Mamba) / [Mamba for medical image analysis](https://mlsanity.com/ssm/mamba-for-medical-image-analysis/)

## Builds on (most cited first, 14 of 14)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Mamba: Linear-Time Sequence Modeling with Selective State Spaces](https://mlsanity.com/paper/2312.00752/) (2023)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutions](https://mlsanity.com/paper/2102.12122/) (2021)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Model](https://mlsanity.com/paper/2401.09417/) (2024)
- [MaxViT: Multi-Axis Vision Transformer](https://mlsanity.com/paper/2204.01697/) (2022)
- [U-Mamba: Enhancing Long-range Dependency for Biomedical Image Segmentation](https://mlsanity.com/paper/2401.04722/) (2024)
- [UniFormer: Unifying Convolution and Self-attention for Visual Recognition](https://mlsanity.com/paper/2201.09450/) (2022)
- [FLatten Transformer: Vision Transformer using Focused Linear Attention](https://mlsanity.com/paper/2308.00442/) (2023)
- [Can recurrent neural networks warp time?](https://mlsanity.com/paper/1804.11188/) (2018)
- [SpectFormer: Frequency and Attention is what you need in a Vision Transformer](https://mlsanity.com/paper/2304.06446/) (2023)
- [CMU-Net: A Strong ConvMixer-based Medical Ultrasound Image Segmentation Network](https://mlsanity.com/paper/2210.13012/) (2022)
- [Image Segmentation Keras : Implementation of Segnet, FCN, UNet, PSPNet and other models in Keras](https://mlsanity.com/paper/2307.13215/) (2023)

## Built on by (most cited first, 21 of 21)

- [Mamba-360: Survey of State Space Models as Transformer Alternative for Long Sequence Modelling: Methods, Applications, and Challenges](https://mlsanity.com/paper/2404.16112/) (2024)
- [MiM-ISTD: Mamba-in-Mamba for Efficient Infrared Small Target Detection](https://mlsanity.com/paper/2403.02148/) (2024)
- [State Space Model for New-Generation Network Alternative to Transformers: A Survey](https://mlsanity.com/paper/2404.09516/) (2024)
- [Vision Mamba: A Comprehensive Survey and Taxonomy](https://mlsanity.com/paper/2405.04404/) (2024)
- [A Survey on Visual Mamba](https://mlsanity.com/paper/2404.15956/) (2024)
- [Visual Mamba: A Survey and New Outlooks](https://mlsanity.com/paper/2404.18861/) (2024)
- [A Survey of Mamba](https://mlsanity.com/paper/2408.01129/) (2024)
- [Mamba in Vision: A Comprehensive Survey of Techniques and Applications](https://mlsanity.com/paper/2410.03105/) (2024)
- [T-Mamba: A unified framework with Long-Range Dependency in dual-domain for 2D & 3D Tooth Segmentation](https://mlsanity.com/paper/2404.01065/) (2024)
- [A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyond](https://mlsanity.com/paper/2410.02362/) (2024)
- [AVS-Mamba: Exploring Temporal and Multi-modal Mamba for Audio-Visual Segmentation](https://mlsanity.com/paper/2501.07810/) (2025)
- [WeatherGen: A Unified Diverse Weather Generator for LiDAR Point Clouds via Spider Mamba Diffusion](https://mlsanity.com/paper/2504.13561/) (2025)
- [3DMambaComplete: Exploring Structured State Space Model for Point Cloud Completion](https://mlsanity.com/paper/2404.07106/) (2024)
- [MambaUIE&SR: Unraveling the Ocean's Secrets with Only 2.8 GFLOPs](https://mlsanity.com/paper/2404.13884/) (2024)
- [UD-Mamba: A pixel-level uncertainty-driven Mamba model for medical image segmentation](https://mlsanity.com/paper/2502.02024/) (2025)
- [MLLA-UNet: Mamba-like Linear Attention in an Efficient U-Shape Model for Medical Image Segmentation](https://mlsanity.com/paper/2410.23738/) (2024)
- [Technologies on Effectiveness and Efficiency: A Survey of State Spaces Models](https://mlsanity.com/paper/2503.11224/) (2025)
- [TrackingMiM: Efficient Mamba-in-Mamba Serialization for Real-time UAV Object Tracking](https://mlsanity.com/paper/2507.01535/) (2025)
- [Hierarchical Spatio-temporal Segmentation Network for Ejection Fraction Estimation in Echocardiography Videos](https://mlsanity.com/paper/2508.18681/) (2025)
- [FaRMamba: Frequency-based learning and Reconstruction aided Mamba for Medical Segmentation](https://mlsanity.com/paper/2507.20056/) (2025)
- [CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation](https://mlsanity.com/paper/2603.19659/) (2026)

## Abstract (arXiv)

In pediatric cardiology, the accurate and immediate assessment of cardiac function through echocardiography is crucial since it can determine whether urgent intervention is required in many emergencies. However, echocardiography is characterized by ambiguity and heavy background noise interference, causing more difficulty in accurate segmentation. Present methods lack efficiency and are prone to mistakenly segmenting some background noise areas, such as the left ventricular area, due to noise disturbance. To address these issues, we introduce P-Mamba, which integrates the Mixture of Experts (MoE) concept for efficient pediatric echocardiographic left ventricular segmentation. Specifically, we utilize the recently proposed ViM layers from the vision mamba to enhance our model's computational and memory efficiency while modeling global dependencies.In the DWT-based Perona-Malik Diffusion (PMD) Block, we devise a PMD Block for noise suppression while preserving the left ventricle's local shape cues. Consequently, our proposed P-Mamba innovatively combines the PMD's noise suppression and local feature extraction capabilities with Mamba's efficient design for global dependency modeling. We conducted segmentation experiments on two pediatric ultrasound datasets and a general ultrasound dataset, namely Echonet-dynamic, and achieved state-of-the-art (SOTA) results. Leveraging the strengths of the P-Mamba block, our model demonstrates superior accuracy and efficiency compared to established models, including vision transformers with quadratic and linear computational complexity.
