# Large Language Model based Multi-Agents: A Survey of Progress and Challenges

arXiv: https://arxiv.org/abs/2402.01680 · HTML: https://mlsanity.com/paper/2402.01680/

## Key facts

- Cited by 769 papers in the map (data through 14 Oct 2026).
- Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use.
- Builds on 65 of its 87 references that are in the map.
- First posted on arXiv 21 Jan 2024.

## Placed in

- LLM agents and tool use / [General LLM agent frameworks and benchmarks](https://mlsanity.com/agents/general-llm-agent-frameworks-and-benchmarks/)

## Builds on (most cited first, 30 of 65)

- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Training Verifiers to Solve Math Word Problems](https://mlsanity.com/paper/2110.14168/) (2021)
- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Measuring Massive Multitask Language Understanding](https://mlsanity.com/paper/2009.03300/) (2020)
- [Reflexion: Language Agents with Verbal Reinforcement Learning](https://mlsanity.com/paper/2303.11366/) (2023)
- [Generative Agents: Interactive Simulacra of Human Behavior](https://mlsanity.com/paper/2304.03442/) (2023)
- [Tree of Thoughts: Deliberate Problem Solving with Large Language Models](https://mlsanity.com/paper/2305.10601/) (2023)
- [A Survey on Large Language Model based Autonomous Agents](https://mlsanity.com/paper/2308.11432/) (2023)
- [Retrieval-Augmented Generation for Large Language Models: A Survey](https://mlsanity.com/paper/2312.10997/) (2023)
- [MetaGPT: Meta Programming for A Multi-Agent Collaborative Framework](https://mlsanity.com/paper/2308.00352/) (2023)
- [Improving Factuality and Reasoning in Language Models through Multiagent Debate](https://mlsanity.com/paper/2305.14325/) (2023)
- [A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questions](https://mlsanity.com/paper/2311.05232/) (2023)
- [The Rise and Potential of Large Language Model Based Agents: A Survey](https://mlsanity.com/paper/2309.07864/) (2023)
- [Did Aristotle Use a Laptop? A Question Answering Benchmark with Implicit Reasoning Strategies](https://mlsanity.com/paper/2101.02235/) (2021)
- [ChatEval: Towards Better LLM-based Evaluators through Multi-Agent Debate](https://mlsanity.com/paper/2308.07201/) (2023)
- [AgentVerse: Facilitating Multi-Agent Collaboration and Exploring Emergent Behaviors](https://mlsanity.com/paper/2308.10848/) (2023)
- [API-Bank: A Comprehensive Benchmark for Tool-Augmented LLMs](https://mlsanity.com/paper/2304.08244/) (2023)
- [Decomposed Prompting: A Modular Approach for Solving Complex Tasks](https://mlsanity.com/paper/2210.02406/) (2022)
- [Using Large Language Models to Simulate Multiple Humans and Replicate Human Subject Studies](https://mlsanity.com/paper/2208.10264/) (2022)
- [Cognitive Architectures for Language Agents](https://mlsanity.com/paper/2309.02427/) (2023)
- [SOTOPIA: Interactive Evaluation for Social Intelligence in Language Agents](https://mlsanity.com/paper/2310.11667/) (2023)
- [MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoning](https://mlsanity.com/paper/2311.10537/) (2023)
- [Social Simulacra: Creating Populated Prototypes for Social Computing Systems](https://mlsanity.com/paper/2208.04024/) (2022)
- [A Dynamic LLM-Powered Agent Network for Task-Oriented Agent Collaboration](https://mlsanity.com/paper/2310.02170/) (2023)
- [Self-collaboration Code Generation via ChatGPT](https://mlsanity.com/paper/2304.07590/) (2023)
- [Can Large Language Models Transform Computational Social Science?](https://mlsanity.com/paper/2305.03514/) (2023)
- [Exploring Large Language Models for Communication Games: An Empirical Study on Werewolf](https://mlsanity.com/paper/2309.04658/) (2023)
- [Building Cooperative Embodied Agents Modularly with Large Language Models](https://mlsanity.com/paper/2307.02485/) (2023)
- [S3: Social-network Simulation System with Large Language Model-Empowered Agents](https://mlsanity.com/paper/2307.14984/) (2023)
- [Exploring Collaboration Mechanisms for LLM Agents: A Social Psychology View](https://mlsanity.com/paper/2310.02124/) (2023)

## Built on by (most cited first, 30 of 769)

- [A Survey on the Memory Mechanism of Large Language Model based Agents](https://mlsanity.com/paper/2404.13501/) (2024)
- [Why Do Multi-Agent LLM Systems Fail?](https://mlsanity.com/paper/2503.13657/) (2025)
- [Justice or Prejudice? Quantifying Biases in LLM-as-a-Judge](https://mlsanity.com/paper/2410.02736/) (2024)
- [Magentic-One: A Generalist Multi-Agent System for Solving Complex Tasks](https://mlsanity.com/paper/2411.04468/) (2024)
- [Data Interpreter: An LLM Agent For Data Science](https://mlsanity.com/paper/2402.18679/) (2024)
- [AgentSpec: Customizable Runtime Enforcement for Safe and Reliable LLM Agents](https://mlsanity.com/paper/2503.18666/) (2025)
- [Chain of Agents: Large Language Models Collaborating on Long-Context Tasks](https://mlsanity.com/paper/2406.02818/) (2024)
- [A Survey on Efficient Inference for Large Language Models](https://mlsanity.com/paper/2404.14294/) (2024)
- [Large Language Model Agent: A Survey on Methodology, Applications and Challenges](https://mlsanity.com/paper/2503.21460/) (2025)
- [Large Language Model-Based Agents for Software Engineering: A Survey](https://mlsanity.com/paper/2409.02977/) (2024)
- [Large Language Model-Brained GUI Agents: A Survey](https://mlsanity.com/paper/2411.18279/) (2024)
- [From LLM Reasoning to Autonomous AI Agents: A Comprehensive Review](https://mlsanity.com/paper/2504.19678/) (2025)
- [Cut the Crap: An Economical Communication Pipeline for LLM-based Multi-Agent Systems](https://mlsanity.com/paper/2410.02506/) (2024)
- [Towards a Science of Scaling Agent Systems](https://mlsanity.com/paper/2512.08296/) (2025)
- [Prompt Infection: LLM-to-LLM Prompt Injection within Multi-Agent Systems](https://mlsanity.com/paper/2410.07283/) (2024)
- [OWL: Optimized Workforce Learning for General Multi-Agent Assistance in Real-World Task Automation](https://mlsanity.com/paper/2505.23885/) (2025)
- [SoK: Agentic Skills -- Beyond Tool Use in LLM Agents](https://mlsanity.com/paper/2602.20867/) (2026)
- [Emergent social conventions and collective bias in LLM populations](https://mlsanity.com/paper/2410.08948/) (2024)
- [G-Memory: Tracing Hierarchical Memory for Multi-Agent Systems](https://mlsanity.com/paper/2506.07398/) (2025)
- [WebShaper: Agentically Data Synthesizing via Information-Seeking Formalization](https://mlsanity.com/paper/2507.15061/) (2025)
- [Empowering Biomedical Discovery with AI Agents](https://mlsanity.com/paper/2404.02831/) (2024)
- [A Comprehensive Survey in LLM(-Agent) Full Stack Safety: Data, Training and Deployment](https://mlsanity.com/paper/2504.15585/) (2025)
- [A Survey of Frontiers in LLM Reasoning: Inference Scaling, Learning to Reason, and Agentic Systems](https://mlsanity.com/paper/2504.09037/) (2025)
- [Recursive Language Models](https://mlsanity.com/paper/2512.24601/) (2025)
- [A survey of agent interoperability protocols: Model Context Protocol (MCP), Agent Communication Protocol (ACP), Agent-to-Agent Protocol (A2A), and Agent Network Protocol (ANP)](https://mlsanity.com/paper/2505.02279/) (2025)
- [LLM as a Mastermind: A Survey of Strategic Reasoning with Large Language Models](https://mlsanity.com/paper/2404.01230/) (2024)
- [Agent KB: Leveraging Cross-Domain Experience for Agentic Problem Solving](https://mlsanity.com/paper/2507.06229/) (2025)
- [LLM Hallucinations in Practical Code Generation: Phenomena, Mechanism, and Mitigation](https://mlsanity.com/paper/2409.20550/) (2024)
- [A Survey of Large Language Models for Financial Applications: Progress, Prospects and Challenges](https://mlsanity.com/paper/2406.11903/) (2024)
- [AgentNet: Decentralized Evolutionary Coordination for LLM-based Multi-Agent Systems](https://mlsanity.com/paper/2504.00587/) (2025)

## Abstract (arXiv)

Large Language Models (LLMs) have achieved remarkable success across a wide array of tasks. Due to the impressive planning and reasoning abilities of LLMs, they have been used as autonomous agents to do many tasks automatically. Recently, based on the development of using one LLM as a single planning or decision-making agent, LLM-based multi-agent systems have achieved considerable progress in complex problem-solving and world simulation. To provide the community with an overview of this dynamic field, we present this survey to offer an in-depth discussion on the essential aspects of multi-agent systems based on LLMs, as well as the challenges. Our goal is for readers to gain substantial insights on the following questions: What domains and environments do LLM-based multi-agents simulate? How are these agents profiled and how do they communicate? What mechanisms contribute to the growth of agents' capacities? For those interested in delving into this field of study, we also summarize the commonly used datasets or benchmarks for them to have convenient access. To keep researchers updated on the latest studies, we maintain an open-source GitHub repository, dedicated to outlining the research on LLM-based multi-agent systems.