# Interpretation of Intracardiac Electrograms Through Textual Representations

arXiv: https://arxiv.org/abs/2402.01115 · HTML: https://mlsanity.com/paper/2402.01115/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 17 of its 43 references that are in the map.
- First posted on arXiv 2 Feb 2024.

## Builds on (most cited first, 17 of 17)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [BEiT: BERT Pre-Training of Image Transformers](https://mlsanity.com/paper/2106.08254/) (2021)
- [Big Bird: Transformers for Longer Sequences](https://mlsanity.com/paper/2007.14062/) (2020)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Attention is not Explanation](https://mlsanity.com/paper/1902.10186/) (2019)
- [Attention is not not Explanation](https://mlsanity.com/paper/1908.04626/) (2019)
- [CausaLM: Causal Model Explanation Through Counterfactual Language Models](https://mlsanity.com/paper/2005.13407/) (2020)
- [Causal Machine Learning for Healthcare and Precision Medicine](https://mlsanity.com/paper/2205.11402/) (2022)
- [Transformers are uninterpretable with myopic methods: a case study with bounded Dyck grammars](https://mlsanity.com/paper/2312.01429/) (2023)
- [Transfer Knowledge from Natural Language to Electrocardiography: Can We Detect Cardiovascular Disease Through Language Models?](https://mlsanity.com/paper/2301.09017/) (2023)
- [Explainable Deep Learning in Healthcare: A Methodological Survey from an Attribution View](https://mlsanity.com/paper/2112.02625/) (2021)
- [Towards a Comprehensive Human-Centred Evaluation Framework for Explainable AI](https://mlsanity.com/paper/2308.06274/) (2023)
- [RT-RCG: Neural Network and Accelerator Search Towards Effective and Real-time ECG Reconstruction from Intracardiac Electrograms](https://mlsanity.com/paper/2111.02569/) (2021)

## Built on by (most cited first, 2 of 2)

- [ECG-Byte: A Tokenizer for End-to-End Generative Electrocardiogram Language Modeling](https://mlsanity.com/paper/2412.14373/) (2024)
- [Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Framework](https://mlsanity.com/paper/2505.18847/) (2025)

## Abstract (arXiv)

Understanding the irregular electrical activity of atrial fibrillation (AFib) has been a key challenge in electrocardiography. For serious cases of AFib, catheter ablations are performed to collect intracardiac electrograms (EGMs). EGMs offer intricately detailed and localized electrical activity of the heart and are an ideal modality for interpretable cardiac studies. Recent advancements in artificial intelligence (AI) has allowed some works to utilize deep learning frameworks to interpret EGMs during AFib. Additionally, language models (LMs) have shown exceptional performance in being able to generalize to unseen domains, especially in healthcare. In this study, we are the first to leverage pretrained LMs for finetuning of EGM interpolation and AFib classification via masked language modeling. We formulate the EGM as a textual sequence and present competitive performances on AFib classification compared against other representations. Lastly, we provide a comprehensive interpretability study to provide a multi-perspective intuition of the model's behavior, which could greatly benefit the clinical use.